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🧬 AGENCY FEED

NIH — National Institutes of Health

NIH is the primary federal agency for biomedical and behavioral research, funding thousands of grants across disease research, clinical trials, and public health.

ACTIVE GRANTS: 391 // TOTAL CAPACITY: $259,001,998 // STATUS: LIVE
Mission

To seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability.

Established 1887
Annual Budget $47 billion
Active Grants 391
Total Capacity $259,001,998

National Institutes of Health: Key Programs & Funding Mechanisms

R01 Research Project Grant
The most common NIH grant — supports discrete, specified research projects.
SBIR/STTR
Small Business Innovation Research and Technology Transfer programs for commercialization.
R21 Exploratory Research
Supports new, exploratory and developmental research projects.
F Series Fellowships
Individual fellowships for predoctoral and postdoctoral training.
P Series Program Project
Supports broadly based, long-term research programs with multiple investigators.

Active NIH Grant Opportunities

SEC_ID: PAR-25-274 11/17/2026
Feasibility Clinical Trials of Mind and Body Interventions for NCCIH High Priority Research Topics (R34 Clinical Trial Required)
Award Agency Discretion

The goal of this notice of funding opportunity (NOFO) is to support feasibility trials of complementary and integrative health app...

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SEC_ID: PAR-24-276 07/14/2026
Data Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Mind and Body Interventions (Collaborative U24 Clinical Trial Required)
Award Agency Discretion

This notice of funding opportunity (NOFO), utilizing the U24 grant funding mechanism, encourages applications for a collaborating ...

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SEC_ID: PAR-25-268 11/17/2026
Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth (R01 Clinical Trial Required)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated fully remotely delivered and conducte...

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SEC_ID: PAR-25-155 10/19/2026
Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional)
Award $50,000

The purpose of this NOFO is to enhance the capability of NCATS CTSA Program KL2 scholars and recipients of re-entry supplements su...

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SEC_ID: PAR-25-144 01/07/2028
Dissemination and Implementation Research in Health (R01 Clinical Trial Optional)
Award Agency Discretion

The purpose of this Notice of Funding Opportunity (NOFO) is to support studies that will identify, develop, and/or test strategies...

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SEC_ID: PAR-25-143 01/07/2028
Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)
Award Agency Discretion

The purpose of this Funding Opportunity Announcement (FOA) is to support studies that will identify, develop, and/or test strategi...

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SEC_ID: PAR-25-233 01/07/2028
Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of this Funding Opportunity Announcement (FOA) is to support studies that will identify, develop, and/or test strategi...

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SEC_ID: PAR-25-221 01/07/2027
Population Approaches to Reducing Alcohol-related Cancer Risk (R01 Clinical Trial Optional)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) aims to support research on interdisciplinary population approaches to increasing awaren...

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SEC_ID: RFA-CA-24-026 09/28/2026
National Cancer Institute Youth Enjoy Science Research Education Program (R25 Clinical Trial Not Allowed)
Award $400,000

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching g...

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SEC_ID: RFA-OD-24-007 07/01/2026
INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Predoctoral to Postdoctoral Fellow Transition Award (F99/K00 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of the INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Predoctoral ...

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SEC_ID: PAR-23-197 06/09/2026
NEI Institutional Mentored Physician Scientist Award (K12 Clinical Trial Optional)
Award Agency Discretion

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage institutions to propose creative and innovative instituti...

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SEC_ID: PAR-23-228 09/25/2026
National Institute of General Medical Sciences Predoctoral Basic Biomedical Sciences Research Training Program (T32)
Award Agency Discretion

The goal of the NIGMS Predoctoral Basic Biomedical Sciences Research Training Program is to develop a pool of well-trained scienti...

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SEC_ID: PA-24-175 05/07/2027
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)
Award Agency Discretion

The purpose of the NIH Mentored Research Scientist Development Award (K01) is to provide support and protected time (three to five...

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SEC_ID: PAR-25-286 01/07/2028
Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R21 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage applications seeking to develop the next generation of br...

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SEC_ID: RFA-MH-25-105 07/01/2026
BRAIN Initiative: Production and distribution facilities for brain cell type-specific access reagents (U24 Clinical Trial Not Allowed)
Award Agency Discretion

This BRAIN Initiative Notice of Funding Opportunity (NOFO) is to support scaled reagent production and distribution facilities inv...

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SEC_ID: PAR-25-101 08/11/2027
Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)
Award $150,000

The National Institute on Drug Abuse (NIDA) Cutting-Edge Basic Research Award (CEBRA) is designed to foster highly innovative or c...

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SEC_ID: PAR-25-347 09/07/2026
Substance Use/Substance Use Disorder Dissertation Research Award (R36 Clinical Trials Not Allowed)
Award Agency Discretion

The goal of this NOFO is to support doctoral candidates from a variety of academic disciplines for up to two years for the complet...

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SEC_ID: PAR-25-247 09/25/2026
Institutional Training Programs to Advance Translational Research on Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) (T32 Clinical Trial Not Allowed)
Award Agency Discretion

The specific purpose of this Notice of Funding Opportunity (NOFO) is to promote the development of a diverse, interdisciplinary wo...

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SEC_ID: PAR-25-317 05/08/2027
Risk and Protective Factors of Family Health and Family Level Interventions (R01 Clinical Trial Optional)
Award Agency Discretion

The purpose of this initiative is to advance the science of minority health and health disparities by supporting research on famil...

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SEC_ID: RFA-NS-25-016 06/17/2026
BRAIN Initiative: Promoting Health for All Through BRAIN Technology Partnerships (R34 - Clinical Trials Not Allowed)
Award Agency Discretion

The goal of this concept is to increase the impact of the BRAIN Initiative by targeted dissemination and integration of validated ...

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SEC_ID: PAR-25-156 09/28/2026
Limited Competition: High Impact Specialized Innovation Programs in Clinical and Translational Science (RC2 Clinical Trials Optional)
Award Agency Discretion

The purpose of the High Impact Specialized Innovation Programs (SIPs) is to support the development and demonstration of unique hu...

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SEC_ID: PAR-25-298 01/07/2028
Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)
Award $375,000

The purpose of the Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools is to stimulate ...

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SEC_ID: PAR-25-370 11/16/2026
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)
Award $50,000

The purpose of this Notice of Funding Opportunity (NOFO) is to invite Small Research Grant (R21) applications that propose to stud...

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SEC_ID: PAR-26-001 05/07/2027
Screening, Brief Intervention and Referral to Treatment or Prevention (SBIRT/P) for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities (R01, Clinical Trial Required)
Award Agency Discretion

The Office of Disease Prevention (ODP) and participating National Institutes of Health (NIH) Institutes, Centers, and Offices (ICO...

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SEC_ID: PAR-25-098 01/07/2027
Interventions to expand cancer screening and preventive services to ADVANCE health in populations that experience health disparities (R01, Clinical Trial Required)
Award Agency Discretion

The Office of Disease Prevention (ODP) and participating National Institutes of Health (NIH) Institutes, Centers, and Offices (ICs...

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SEC_ID: PAR-24-127 09/29/2026
NIDCD's Mentored Research Education Pathway for Otolaryngology Residents and Medical Students (R25 - Clinical Trial Not Allowed)
Award $499,999

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching g...

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SEC_ID: PAR-24-281 05/25/2026
NLM Information Resource Grants to Reduce Health Disparities and Promote Health for All (G08 Clinical Trial Not Allowed)
Award $200,000

This Notice of Funding Opportunity Announcement (NOFO) solicits resource grant applications for projects that will provide accurat...

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SEC_ID: PAR-25-311 11/15/2027
Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Women, and Persons with Disabilities (UG3/UH3 - Clinical Trial Optional)
Award $6,250,000

The purpose of this Notice of Funding Opportunity (NOFO) is to leverage NICHD clinical research Network infrastructure relevant to...

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SEC_ID: PAR-25-371 11/18/2026
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)
Award Agency Discretion

The purpose of this NOFO is to invite Research Project (R01) applications that propose to study the ethical, legal, and social imp...

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SEC_ID: PAR-25-020 09/29/2027
Research Experiences and/or Mentoring Networks through Research Education to Enhance Clinician-Scientists' Participation in NIDCDs Research (R25 Clinical Trial Not Allowed)
Award $250,000

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching g...

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SEC_ID: PAR-25-369 11/18/2026
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)
Award Agency Discretion

The purpose of this NOFO is to invite Exploratory/Developmental Research Grant (R21) applications that propose to study the ethica...

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SEC_ID: PAR-25-378 01/07/2027
Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)
Award Agency Discretion

The purpose of this notice of funding opportunity (NOFO) is to support research on interventions to improve health in Native Ameri...

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SEC_ID: RFA-OD-25-003 04/09/2027
Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Clinical Trials Not Allowed)
Award $200,000

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching g...

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SEC_ID: PAR-25-383 01/28/2028
Blueprint MedTech Translator (UG3/UH3 - Clinical Trial Optional)
Award Agency Discretion

The purpose of this announcement is to encourage investigators to pursue translational activities and clinical feasibility studies...

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SEC_ID: PAR-25-333 05/07/2028
NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of the NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00) program is to develop and maintain ...

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SEC_ID: RFA-OD-25-008 07/14/2026
Tobacco Regulatory Science Small Grant Program for New Investigators (R03 Clinical Trial Optional)
Award $75,000

This Notice of Funding Opportunity (NOFO) aims to support new biomedical, behavioral, and social science investigators who are in ...

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SEC_ID: PA-25-168 05/04/2028
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32)
Award Agency Discretion

The National Institutes of Health (NIH) will award Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Resear...

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SEC_ID: PAR-25-416 06/14/2027
NIGMS National and Regional Resources (R24 - Clinical Trial Not Allowed)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) encourages applications for support of resources that will provide access to state-of-th...

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SEC_ID: PAR-25-379 01/07/2027
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)
Award Agency Discretion

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SEC_ID: PA-25-425 05/07/2028
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) will support students at institutions without NIH-funded institutional predoctoral dual-...

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SEC_ID: PA-25-426 05/07/2028
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) will support students at institutions with NIH-funded institutional predoctoral dual-deg...

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SEC_ID: PA-25-422 05/07/2028
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31)
Award Agency Discretion

The purpose of the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral (Parent F31) award is to enab...

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SEC_ID: PA-25-424 05/07/2028
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33)
Award Agency Discretion

The National Institutes of Health (NIH) awards senior individual research training fellowships to experienced scientists who wish ...

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SEC_ID: PAR-25-415 09/07/2028
Support for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed)
Award $125,000

The SuRE program supports research capacity building at eligible higher education institutions through funding investigator-initia...

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SEC_ID: PAR-25-414 09/07/2028
Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed)
Award $100,000

The SuRE program supports research capacity building at eligible higher education institutions by funding investigator-initiated b...

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SEC_ID: PA-25-423 05/07/2028
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32)
Award Agency Discretion

The purpose of the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32) is t...

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SEC_ID: PAR-24-120 07/13/2026
NIA Career Transition Award (K22 Independent Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of the NIA Career Transition Award (CTA) is to facilitate the transition of mentored researchers to tenure-track facul...

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SEC_ID: PAR-25-157 06/18/2026
Awards Supporting Cutting-Edge Technologies for Translational Science (ASCETTS) (R21 Clinical Trials Not Allowed)
Award Agency Discretion

The National Center for Advancing Translational Sciences (NCATS) invites applications for the Awards Supporting Cutting-Edge Techn...

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SEC_ID: PAR-25-437 03/01/2028
Environmental influences on Child Health Outcomes (ECHO) Cohort Data and Biospecimen Access (X01 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of this Program Announcement with Special Receipt, Referral, and/or Review Considerations (PAR) is to solicit applicat...

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SEC_ID: PAR-23-284 09/25/2026
Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2024, 2025, and 2026 (P50 Clinical Trial Required)
Award Agency Discretion

Through this funding opportunity announcement (FOA), the National Cancer Institute (NCI) invites applications for P50 Research Cen...

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SEC_ID: PAR-23-287 10/14/2026
NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Required)
Award Agency Discretion

The purpose of the NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00) program is to increase and...

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SEC_ID: PAR-24-065 09/25/2026
NHLBI Program Project Applications (P01 Clinical Trials Optional)
Award Agency Discretion

The National Heart, Lung, and Blood Institute (NHLBI) Program Project Grant (P01) supports research related to fundamental process...

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SEC_ID: PAR-23-235 09/07/2026
National Centers for Biomedical Imaging and Bioengineering (NCBIB) (P41 Clinical Trials Optional)
Award Agency Discretion

This Funding Opportunity Announcement (FOA) encourages grant applications for Biomedical Technology Resource Centers (BTRCs). BTRC...

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SEC_ID: PAR-23-276 01/07/2027
Cancer Research Education Grants Program - Courses for Skills Development (R25 Clinical Trial Not Allowed)
Award $300,000

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching ...

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SEC_ID: PAR-23-277 01/07/2027
Cancer Research Education Grants Program - Research Experiences (R25 Clinical Trial Not Allowed)
Award $300,000

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching ...

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SEC_ID: PAR-24-071 09/25/2026
Alcohol Research-Related Resource Award (R24 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of the Resource-Related Research Projects (R24) grant is to support investigator-initiated resources designed to provi...

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SEC_ID: PA-24-191 05/07/2027
Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of the Mentored Quantitative Research Career Development Award (K25) is to attract to NIH-relevant research those inve...

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SEC_ID: PA-24-193 05/07/2027
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required)
Award Agency Discretion

The purpose of the NIH Pathway to Independence Award (K99/R00) program is to increase and maintain a strong cohort of new and tale...

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SEC_ID: RFA-MH-25-110 06/24/2026
BRAIN Initiative: Data Archives for the BRAIN Initiative (R24 Clinical Trial Optional)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) solicits applications to develop web-accessible data archives to capture, store, and cur...

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SEC_ID: PAR-25-203 01/07/2028
Focused Technology Research and Development (R01 Clinical Trial Not Allowed)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) supports projects relevant to the NIGMS mission that focus solely on the development of ...

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SEC_ID: PAR-25-227 01/07/2028
Natural History of Disorders Screenable in the Newborn Period (R01 Clinical Trial Optional)
Award Agency Discretion

The purpose of this Notice of Funding Opportunity (NOFO) encourages applications that will expand knowledge of the natural history...

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SEC_ID: PAR-25-038 09/07/2026
Cellular and Molecular Biology of Complex Brain Disorders (R01 Clinical Trial Not Allowed)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) encourages research on the biology of high-confidence risk factors associated with compl...

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SEC_ID: PAR-25-053 01/28/2027
Translational Neural Devices (R61/R33 - Clinical Trial Optional)
Award Agency Discretion

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage investigators to pursue translational activities and smal...

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SEC_ID: PAR-25-066 09/07/2026
Social disconnection and Suicide Risk in Late Life (R21 Clinical Trial Optional)
Award Agency Discretion

This initiative seeks to solicit applications for research projects that address the link between social disconnection including b...

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SEC_ID: PA-24-254 07/12/2027
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)
Award Agency Discretion

The National Institutes of Health (NIH) hereby notifies recipient organizations holding specific types of NIH grants, listed withi...

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SEC_ID: PAR-25-103 10/25/2027
Cancer Prevention and Control Clinical Trials Planning Grant Program (U34 Clinical Trials Optional)
Award Agency Discretion

The purpose of this NOFO is to facilitate well planned clinical trials across the cancer prevention and control spectrum aimed at ...

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SEC_ID: PAR-25-202 01/07/2028
Technology Development Research for Establishing Feasibility and Proof of Concept (R21 - Clinical Trial Not Allowed)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO)supports exploratory research leading to proof of concept for the development of new tech...

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SEC_ID: PAR-24-293 08/18/2027
Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)
Award Agency Discretion

The Blueprint Neurotherapeutics Network for Biologics (BPN-Biologics) provides support for biologic-based therapeutic discovery an...

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SEC_ID: PAR-24-295 12/03/2026
Emerging Global Leader Award (K43 Independent Clinical Trial Required)
Award Agency Discretion

This is a reissue of the Emerging Global Leader Program (K43) to align with the clinical trials policy.

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SEC_ID: PAR-25-145 01/07/2028
Clinical Characterization of Cancer Therapy-induced Adverse Sequelae and Mechanism-based Interventional Strategies (R01 Clinical Trial Optional)
Award Agency Discretion

The purpose of this Funding Opportunity Announcement (FOA) is to support collaborative research projects designed to address adver...

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SEC_ID: PAR-25-050 06/22/2026
Analytical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders(U01 Clinical Trial Optional)
Award Agency Discretion

The purpose of this notice of funding opportunity (NOFO) is to support rigorous analytical validation of method(s) used for measur...

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SEC_ID: PAR-24-211 07/12/2027
NHLBI Career Transition Award for Intramural Postdoctoral Fellows and Research Trainees (K22 Clinical Trial Required)
Award Agency Discretion

The purpose of the NHLBI Career Transition Award (K22) program is to provide highly qualified postdoctoral fellows in the NHLBI Di...

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SEC_ID: PAR-25-256 01/07/2027
Developing novel theory and methods for understanding the genetic architecture of complex human traits (R21 Clinical Trial Not Allowed)
Award Agency Discretion

The goal of this NOFO is to support R21 applications for novel theory and methods development that better delineate how genetic an...

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SEC_ID: PAR-25-136 01/07/2028
Laboratories to Optimize Digital Health (R01 Clinical Trial Required)
Award Agency Discretion

NIMH seeks applications for innovative research projects to test strategies to increase the reach, efficiency, effectiveness, and ...

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SEC_ID: PAR-25-273 01/07/2028
Development of Animal Models and Related Biological Materials for Research (R21 Clinical Trial Not Allowed)
Award $200,000

This notice of funding opportunity (NOFO) encourages innovative research to develop, improve, characterize, and preserve animal mo...

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SEC_ID: PAR-25-027 01/07/2028
NIDCR Dentist Scientist Career Transition Award for Intramural Investigators (K22 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of the NIDCR Dentist Scientist Career Transition Award for Intramural Investigators (K22) program is to facilitate tra...

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SEC_ID: PAR-24-312 07/14/2026
Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Natural Products (Collaborative UG3/UH3 Clinical Trial Required)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) encourages cooperative agreement applications for investigator-initiated, multi-site, cl...

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SEC_ID: PAR-24-313 07/14/2026
Natural Product Multi-Site Clinical Trial Data Coordinating Center (Collaborative U24 Clinical Trial Required)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO), utilizing the U24 grant funding mechanism, encourages applications for a collaborating ...

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SEC_ID: PAR-25-043 01/07/2028
Mechanisms that Impact Cancer Risk after Bariatric Surgery (R01 Clinical Trial Optional)
Award $500,000

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications for support of investi...

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SEC_ID: PAR-25-225 10/20/2027
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Neurotherapeutic Agent Characterization and In vivo Efficacy Studies (R61/R33 Clinical Trial Not Allowed)
Award Agency Discretion

Reissue PAR-21-122. This NOFO provides funding to conduct pharmacodynamic, pharmacokinetic, and in vivo efficacy studies to demons...

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SEC_ID: PAR-25-204 11/12/2027
NIDA Research Education Program for Clinical Researchers and Clinicians (R25 Clinical Trial Not Allowed)
Award $350,000

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching ...

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SEC_ID: RFA-NS-25-022 09/28/2026
BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UH3 Clinical Trial Optional)
Award Agency Discretion

The purpose of this announcement is to encourage investigators to pursue a small clinical trial to obtain critical information nec...

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SEC_ID: PAR-25-112 09/07/2027
Advancement and Innovation in Measurement of Language Development and Predictors (R01 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of this notice of funding opportunity (NOFO) is to encourage community-engaged research that broadens the conceptualiz...

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SEC_ID: PAR-24-235 01/25/2027
Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) Program (UE5/T32)
Award Agency Discretion

The purpose of the Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) program is to fund feder...

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SEC_ID: PAR-25-149 11/05/2027
Limited Competition: Renewal of Existing NINDS-Supported Clinical Trial Cooperative Agreement Awards (U01 - Clinical Trials Required)
Award Agency Discretion

This limited competition Notice of Funding Opportunity (NOFO) invites renewal applications of existing NINDS-supported clinical tr...

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SEC_ID: PAR-25-024 01/07/2028
Development of Biomarkers or Composite Biomarkers for Neurological and Neuromuscular Disorders (R61/R33 - Clinical Trial Optional)
Award Agency Discretion

The overarching purpose of this Funding Opportunity Announcement (FOA) is to promote the discovery and/or early evaluation of stro...

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SEC_ID: PAR-25-113 09/07/2027
Advancement and Innovation in Measurement of Language Development and Predictors (R21 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of this notice of funding opportunity (NOFO) is to encourage community-engaged research that broadens the conceptualiz...

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SEC_ID: PAR-25-131 04/15/2027
Computational Approaches to Curation at Scale for Biomedical Research Assets (R01 Clinical Trial Not Allowed)
Award $250,000

NLM wishes to accelerate access to, and availability of, secure, complete datasets and computational models that can serve as the ...

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SEC_ID: PAR-24-325 09/07/2027
Bioengineering Partnerships with Industry (U01 Clinical Trial Optional)
Award Agency Discretion

This Funding Opportunity Announcement (FOA) solicits applications from research partnerships formed by academic and industrial inv...

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SEC_ID: PAR-24-306 09/07/2026
Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01 Clinical Trial Not Allowed)
Award $499,000

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications for projects to expand...

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SEC_ID: PAR-24-264 06/01/2027
High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed)
Award Agency Discretion

The High-End Instrumentation (HEI) Grant Program encourages applications from groups of NIH-supported investigators to purchase or...

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SEC_ID: PAR-25-183 10/15/2027
Early Stage Testing of Pharmacologic or Neuromodulatory Device-based Interventions for the Treatment of Mental Disorders (R33- Clinical Trial Required)
Award Agency Discretion

NIMH requires an experimental therapeutics approach for the development and testing of therapeutic interventions, in which studies...

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SEC_ID: PAR-25-104 10/25/2027
Cancer Prevention and Control Clinical Trials Planning Grant Program (R34 Clinical Trials Optional)
Award Agency Discretion

The purpose of this FOA is to facilitate well planned clinical trials across the cancer prevention and control spectrum aimed at i...

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SEC_ID: PAR-25-052 11/19/2026
NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)
Award Agency Discretion

This NOFO encourages applications for multi-site exploratory and confirmatory clinical trials focused on promising interventions; ...

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SEC_ID: PAR-24-301 09/25/2027
NICHD Resource Program Grants in Bioinformatics (P41 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of this Notice of Funding Opportunity (NOFO) is to support the continued operation, maintenance, and dissemination of ...

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SEC_ID: PAR-25-265 11/16/2027
Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R01 - Clinical Trial Optional)
Award Agency Discretion

This FOA encourages research relevant to the development of novel screening approaches and/or therapeutic interventions for potent...

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SEC_ID: PAR-25-153 09/07/2026
Assay development and screening for discovery of chemical probes, drugs or immunomodulators (R01 Clinical Trial Not Allowed)
Award Agency Discretion

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for identification of...

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SEC_ID: PAR-25-228 09/07/2027
Investigator Initiated Innovation in Computational Genomics and Data Science (R01 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of this funding opportunity announcement (FOA) is to invite applications for a broad range of research efforts in comp...

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SEC_ID: PAR-25-135 10/14/2027
NCI Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of the NCI Pathway to Independence Award (K99/R00) program is to facilitate a timely transition of talented postdoctor...

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SEC_ID: PAR-25-281 01/07/2028
Mood and Psychosis Symptoms during the Menopause Transition (R01 Clinical Trial Optional)
Award Agency Discretion

The purpose of this Notice of Funding Opportunity (NOFO) is to advance translational research to better understand the emergence a...

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SEC_ID: PAR-25-122 11/16/2027
Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed)
Award $100,000

The purpose of this notice of funding opportunity (NOFO) is to solicit applications for pilot projects to elucidate a role for und...

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SEC_ID: PAR-25-271 11/13/2026
NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required)
Award $350,000

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated mid-phase clinical trials of natural ...

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SEC_ID: PAR-25-267 11/17/2026
NCCIH Multi-Site Feasibility Clinical Trials of Mind and Body Interventions (R01 Clinical Trial Required)
Award $350,000

This notice of funding opportunity (NOFO) invites applications for investigator-initiated clinical trials of complementary and int...

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SEC_ID: PAR-25-248 10/08/2027
Utilizing the PLCO Biospecimens Resource to Bridge Gaps in Cancer Etiology and Early Detection Research (U01 Clinical Trial Not Allowed)
Award Agency Discretion

This Funding Opportunity Announcement (FOA) encourages the submission of applications that propose to advance research in cancer e...

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SEC_ID: PAR-25-148 01/07/2028
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)
Award Agency Discretion

The purpose of this Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions is to support small scale re...

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SEC_ID: RFA-HL-26-019 12/23/2027
Catalyze Product Definition Medical Device prototype design/testing and disease target identification and assay development (R61/R33 - Clinical Trial Not Allowed)
Award Agency Discretion

The goal of the NHLBI Catalyze Program is to provide a comprehensive suite of support and services to facilitate the transition of...

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SEC_ID: PAR-24-311 01/07/2028
Molecular Imaging of Inflammation in Cancer (R01 Clinical Trial Not Allowed)
Award $500,000

The purpose of this Notice of Funding Opportunity (NOFO) is to invite research grant applications (R01) for the development and us...

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SEC_ID: PAR-25-272 05/07/2027
New Approaches for Measuring Brain Changes Across Longer Timespans (R21 Clinical Trial Optional)
Award Agency Discretion

The purpose of this funding opportunity is to encourage multidisciplinary investigators to submit applications developing explorat...

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SEC_ID: PAR-24-268 01/27/2027
Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)
Award $500,000

The Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program aims to promote broad par...

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SEC_ID: PAR-25-251 01/07/2028
NIAID Career Transition Award (K22 Independent Clinical Trial Not Allowed)
Award $150,000

The purpose of the NIAID Career Transition Award program is to assist postdoctoral fellows' transition to positions of assistant p...

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SEC_ID: PAR-25-075 10/14/2026
Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH3 Clinical Trials Not Allowed)
Award $250,000

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to accelerate the adoption and vali...

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SEC_ID: RFA-MH-26-170 02/08/2027
BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications ...

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SEC_ID: PAR-25-285 10/15/2027
Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required)
Award Agency Discretion

This R61/R33 concept complements NIMHs suite of clinical trial NOFOs by supporting feasibility and infrastructure development (R61...

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SEC_ID: PAR-25-177 10/15/2027
Full-Scale Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 - Clinical Trial Required)
Award Agency Discretion

Clinical Trials to Test the Effectiveness of Treatment, Preventive, and Services Interventions (R01 Clinical Trial Required). This...

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SEC_ID: PAR-24-209 07/12/2027
NHLBI Career Transition Award for Intramural Postdoctoral Fellows and Research Trainees (K22 Independent Clinical Trial Not Allowed)
Award Agency Discretion

To provide highly qualified postdoctoral fellows and other doctoral-level researchers currently in training in the NHLBI Division ...

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SEC_ID: PAR-25-181 10/15/2027
Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R33 Clinical Trial Required)
Award Agency Discretion

Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R33 Clinical Trial Required). As part o...

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SEC_ID: PAR-24-275 07/14/2026
Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Mind and Body Interventions (Collaborative UG3/UH3 Clinical Trial Required)
Award Agency Discretion

This notice of funding opportunity (NOFO) encourages applications for investigator-initiated multi site clinical trials (e.g., eff...

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SEC_ID: PAR-25-255 11/05/2026
Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01 Clinical Trial Not Allowed)
Award Agency Discretion

The goal of this NOFO is to support applications for novel theory and methods development that enable better understanding of how ...

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SEC_ID: PAR-25-207 01/07/2028
Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)
Award Agency Discretion

NIMH seeks applications for research projects to evaluate the effectiveness of therapeutic and service delivery interventions for ...

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SEC_ID: PAR-25-229 09/07/2027
Investigator Initiated Innovation in Computational Genomics and Data Science (R21 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of this funding opportunity announcement (FOA) is to invite applications for a broad range of research efforts in comp...

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SEC_ID: PAR-25-105 01/07/2028
NIDCR Small Grant Program for New Investigators (R03 Clinical Trial Not Allowed)
Award Agency Discretion

This NIDCR Small Grant Program for New Investigators supports basic and clinical research conducted by scientists who are in the e...

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SEC_ID: PA-25-125 01/07/2028
NICHD Small Research Grant Program (R03 Clinical Trial Required)
Award $50,000

The NICHD Small Research Grant Program (Clinical Trial Required) supports clinical trials that fall within the NICHD mission.

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SEC_ID: PA-25-245 09/07/2026
Alcohol Health Services Research (R01 Clinical Trial Optional)
Award $500,000

The National Institute on Alcohol Abuse and Alcoholism solicits applications for an R01 Clinical Trial Optional mechanism focusing...

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SEC_ID: PA-25-163 09/07/2026
Alcohol Treatment, Pharmacotherapy, and Recovery Research (R01 Clinical Trial Required)
Award $500,000

The National Institute on Alcohol Abuse and Alcoholism solicits applications for an R01 Clinical Trial Required mechanism focusing...

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SEC_ID: RFA-OD-24-011 12/04/2026
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)
Award Agency Discretion

The purpose of this notice of funding opportunity (NOFO) is to provide salary support for exceptional Research Software Engineers ...

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SEC_ID: PAR-25-175 01/07/2028
Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy (R01 Clinical Trial Optional)
Award $500,000

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) seeks research project (R01) grant applicat...

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SEC_ID: PAR-24-252 10/14/2026
Innovative Programs to Enhance Research Training (IPERT) (R25 Independent Clinical Trial Not Allowed)
Award $500,000

NIGMS will support innovative educational activities designed to equip participants with technical, operational, or professional s...

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SEC_ID: PAR-25-134 01/07/2028
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)
Award $375,000

The purpose of this Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutionsis to support small scale res...

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SEC_ID: RFA-NS-25-023 01/15/2027
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)
Award $350,000

This funding opportunity is part of a suite of NOFOs within the NIH HEAL Initiative to support the development of safe, effective,...

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SEC_ID: PAR-25-291 01/07/2028
Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)
Award $200,000

Reissue of RFA-20-351.The purpose of this Notice of Funding Opportunity (NOFO) is to encourage applications to pursue invasive neu...

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SEC_ID: PAR-25-288 01/07/2028
Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R34 Clinical Trial Required)
Award Agency Discretion

The purpose of this NOFO is to build research about the effectiveness, implementation, and optimization of family navigation ED di...

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SEC_ID: PAR-25-210 06/02/2027
Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional)
Award Agency Discretion

The purpose of this notice of funding opportunity (NOFO) is to support highly innovative mechanistic research to accelerate precis...

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SEC_ID: PAR-24-236 01/25/2027
Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) Program (UE5/T34)
Award Agency Discretion

The purpose of the Tribal Undergraduate to Graduate Research Training and Leadership Experiences (TURTLE) program is to fund feder...

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SEC_ID: PAR-25-192 09/07/2026
Alcohol Health Services Research (R34 Clinical Trial Optional)
Award Agency Discretion

The National Institute on Alcohol Abuse and Alcoholism solicits applications for an R34 Clinical Trial Optional mechanism focusing...

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SEC_ID: PA-25-172 01/07/2028
Modular R01s in Cancer Control and Population Sciences (R01 Clinical Trial Optional)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) encourages applications for research in cancer control and population sciences. The over...

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SEC_ID: PA-25-253 09/07/2028
Exploratory Grants in Cancer Control (R21 Clinical Trial Optional)
Award Agency Discretion

This funding opportunity announcement (FOA) encourages the submission of exploratory/developmental research grant (R21) applicatio...

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SEC_ID: PAR-25-282 01/07/2028
Mood and Psychosis Symptoms during the Menopause Transition (R21 Clinical Trial Optional)
Award Agency Discretion

The purpose of this Notice of Funding Opportunity (NOFO) is to advance translational research to better understand the emergence a...

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SEC_ID: PAR-24-297 01/07/2028
Imaging - Science Track Award for Research Transition (I/START) (R03 Clinical Trial Optional)
Award $150,000

This Notice of Funding Opportunity Announcement (NOFO) is designed to encourage and facilitate the entry of investigators to the a...

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SEC_ID: PAR-25-159 01/07/2027
Prevention and Intervention Approaches for Fetal Alcohol Spectrum Disorders (R34 Clinical Trial Optional)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) for R34 planning grant applications focuses on prevention and intervention strategies fo...

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SEC_ID: PAR-24-204 05/07/2027
Summer Research Education Experience Program (R25 Clinical Trial Not Allowed)
Award Agency Discretion

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching ...

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SEC_ID: PAR-25-279 05/07/2027
New Approaches for Measuring Brain Changes Across Longer Timespans (R01 Clinical Trial Optional)
Award Agency Discretion

The purpose of this funding opportunity is to encourage multidisciplinary investigators to develop new approaches or apply existin...

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SEC_ID: PAR-25-069 01/07/2027
Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R01 Clinical Trial Optional)
Award Agency Discretion

The goal of the proposed funding announcement is twofold, to promote preclinical and patient based studies examining the mechanism...

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SEC_ID: PAR-25-289 01/07/2028
Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R01 Clinical Trial Required)
Award Agency Discretion

The purpose of this NOFO is to build research about the effectiveness, implementation, and optimization of family navigation ED di...

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SEC_ID: PAR-25-310 01/07/2027
Accelerating Solutions to Improve Access and Quality of Empirically-Supported Practices for Youth Mental Health (R01 Clinical Trial Optional)
Award Agency Discretion

This NOFO is a call to action in response to the mental health crisis in the United States. We seek applications that will study m...

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SEC_ID: PAR-24-269 02/11/2027
NIDA Animal Genomics Program (U01 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of the NIDA Animal Genetics Program is to identify genetic, genomic, and molecular (epi)genetic variants that underlie...

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SEC_ID: PAR-25-185 01/07/2028
Screening and Functional Validation of Genomic Variants Associated with Human Congenital Anomalies (R01 Clinical Trial Not Allowed)
Award Agency Discretion

Rapid advances in genotyping and next generation sequencing technologies have led to the identification of genetic variants that a...

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SEC_ID: PAR-25-051 08/18/2026
Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development of Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)
Award Agency Discretion

The Blueprint Neurotherapeutics Network (BPN) invites applications from neuroscience investigators seeking support to advance thei...

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SEC_ID: PAR-25-167 01/07/2027
Cancer Prevention and Control Clinical Trials Grant Program (R01 Clinical Trial Required)
Award Agency Discretion

Through this notice of funding opportunity (NOFO), the National Cancer Institute (NCI) invites applications for support of investi...

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SEC_ID: PAR-25-081 01/07/2027
National Cancer Institute's Investigator-Initiated Early Phase Clinical Trials for Cancer Treatment and Diagnosis (R01 Clinical Trial Required)
Award $499,999

Through this Notice of Funding Opportunity, the National Cancer Institute (NCI) seeks research projects that implement early phase...

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SEC_ID: RFA-NS-25-021 09/28/2026
BRAIN Initiative: Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UG3/UH3 Clinical Trial Optional)
Award Agency Discretion

The purpose of this announcement is to encourage investigators to pursue translational activities and small clinical studies to ad...

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SEC_ID: PA-25-093 01/07/2028
Limited Competition: CCRP Initiative: Promoting a Basic Understanding of Chemical Threats to Skin (R34 Clinical Trial Not Allowed)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) intends to support fundamental research that will contribute to basic understanding of s...

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SEC_ID: PAR-24-321 11/12/2027
NIA Academic Leadership Career Award (K07 Independent Clinical Trial Not Allowed)
Award Agency Discretion

The objective of the NIA Academic Leadership Career Award (K07) is to provide support for established investigators who have the e...

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SEC_ID: PAR-24-326 06/01/2027
Limited Competition: Basic Instrumentation Grant (BIG) Program (S10 Clinical Trial Not Allowed)
Award Agency Discretion

The Basic Instrumentation Grant (BIG) Program encourages applications from groups of NIH-supported investigators to purchase a sin...

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SEC_ID: PAR-25-178 10/15/2027
Pilot Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 Clinical Trial Required)
Award Agency Discretion

Pilot Effectiveness Trials for Treatment, Preventive and Services Interventions (R01 Clinical Trial Required). As part of NIMH's c...

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SEC_ID: PAR-25-179 10/15/2027
Confirmatory Efficacy Clinical Trials of Non-Pharmacological and Pharmacological Interventions for Mental Disorders (R01 Clinical Trial Required)
Award Agency Discretion

Confirmatory Efficacy Clinical Trials of Non-Pharmacological Interventions for Mental Disorders (R01 Clinical Trial Required). As ...

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SEC_ID: RFA-MH-26-140 06/15/2027
BRAIN Initiative: Brain Behavior Quantification and Synchronization- Next Generation Sensor Technology Development (U01 Clinical Trial Optional)
Award Agency Discretion

This NOFO solicits applications for next generation sensor and bioelectronic device development that will synchronize with brain r...

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SEC_ID: PAR-25-025 01/07/2027
NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)
Award $1,515,000

The objective of this funding opportunity is to support investigator-initiated, phase I clinical trials for diagnostic and therape...

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SEC_ID: PAR-24-272 09/28/2027
Clinical and Translational Science Award (UM1 Clinical Trial Optional)
Award Agency Discretion

This Notice of Funding Opportunity announcement (NOFO) invites applications for the Clinical and Translational Science Award (CTSA...

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SEC_ID: PAR-25-188 01/06/2028
NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
Award $500,000

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage UG3/UH3 phased cooperative agreement research application...

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SEC_ID: PAR-25-044 01/07/2028
Mechanisms that Impact Cancer Risk after Bariatric Surgery (R21 Clinical Trial Not Allowed)
Award Agency Discretion

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications for support of investi...

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SEC_ID: PAR-25-026 01/07/2027
NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)
Award Agency Discretion

The objective of this funding opportunity is to support investigator-initiated, Phase I clinical trials for diagnostic and therape...

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SEC_ID: PA-24-253 07/17/2027
Successor-in-Interest (Type 6 Parent Clinical Trial Optional)
Award Agency Discretion

The National Institutes of Health (NIH) hereby notify recipient organizations holding specific types of NIH grants, listed in the ...

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SEC_ID: PAR-25-243 01/07/2028
Basic Research in Cancer Health Disparities (R01 Clinical Trial Not Allowed)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) encourages grant applications from investigators interested in conducting basic, mechani...

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SEC_ID: PAR-25-216 11/12/2027
Career Transition Award for NINDS Intramural Clinician-Scientists (K22 Clinical Trial Required)
Award Agency Discretion

The objective of the NIH Career Transition Award (K22) is to provide support to outstanding basic or clinical investigators to dev...

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SEC_ID: PAR-25-211 06/02/2027
Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional)
Award Agency Discretion

The purpose of this notice of funding opportunity (NOFO) is to support highly innovative mechanistic research to accelerate precis...

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SEC_ID: PAR-25-297 11/05/2027
Alzheimer's Drug-Development Program (U01 Clinical Trial Optional)
Award $1,500,000

The goal of this Notice of Funding Opportunity (NOFO) is to provide funding support for the pre-clinical and early stage clinical ...

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SEC_ID: PAR-25-040 09/07/2026
Schizophrenia and related disorders during mid- to late-life (R21 Clinical Trial Optional)
Award Agency Discretion

Although the majority living with schizophrenia and related disorders are over 35 years old, including those first diagnosed and t...

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SEC_ID: PAR-25-170 06/22/2026
Digital Health Technology Derived Biomarkers and Outcome Assessments for Remote Monitoring and Endpoint Development (UG3/UH3 - Clinical Trial Optional)
Award Agency Discretion

The purpose of this proposed Notice of Funding Announcement (NOFO) is to support development of biomarkers or clinical outcomes de...

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SEC_ID: PAR-25-182 10/15/2027
Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33 Clinical Trial Required)
Award Agency Discretion

Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33 Clinical Trial Required). As pa...

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SEC_ID: PAR-25-095 09/07/2026
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)
Award $350,000

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) along with other participating Institutes e...

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SEC_ID: PAR-25-215 11/12/2027
Career Transition Award for NINDS Intramural Clinician-Scientists (K22 Clinical Trial Not Allowed)
Award Agency Discretion

The objective of the NIH Career Transition Award (K22) is to provide support to outstanding basic or clinical investigators to dev...

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SEC_ID: PAR-25-266 11/16/2027
Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R21 - Clinical Trial Optional)
Award $200,000

This FOA encourages research relevant to the development of novel screening approaches and/or therapeutic interventions for potent...

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SEC_ID: PAR-25-234 01/07/2028
NINDS Ruth L. Kirschstein National Research Service Award (NRSA) for Training of Postdoctoral Fellows (F32 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of this award is to support outstanding scientific training of highly promising postdoctoral candidates with outstandi...

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SEC_ID: PAR-25-065 09/07/2026
Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R01 Clinical Trial Optional)
Award Agency Discretion

The goal of this Funding Opportunity Announcement (FOA) is to encourage applications for studies that will enhance knowledge of me...

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SEC_ID: PAR-25-070 01/07/2027
Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R21 Clinical Trial Not Allowed)
Award Agency Discretion

The goal of the proposed funding announcement is twofold, to promote preclinical and patient based studies examining the mechanism...

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SEC_ID: PAR-25-336 11/15/2027
Toward Translation of Nanotechnology Cancer Interventions (TTNCI; R01 Clinical Trial Not Allowed)
Award Agency Discretion

Through this Notice of Funding Opportunity (NOFO), entitled "Toward Translation of Nanotechnology Cancer Interventions" (TTNCI), t...

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SEC_ID: PA-25-302 01/07/2028
NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed)
Award $50,000

The NIH Small Research Grant Program supports small research projects that can be carried out in a short period of time with limit...

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SEC_ID: PAR-25-196 09/28/2027
Limited Competition: Mentored Research Career Development Program Award in Clinical and Translational Science Awards (CTSA) Program (K12 Clinical Trial Optional)
Award Agency Discretion

The National Center for Advancing Translational Sciences (NCATS) will award Institutional Research Career Development (K12) progra...

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SEC_ID: PAR-25-091 01/07/2028
Limited Competition: Small Grant Program for NIDDK K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)
Award $75,000

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) announces a program that provides NIDDK-supported K01...

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SEC_ID: PAR-25-343 10/18/2027
NIDCD Cooperative Agreement for Clinical Trials in Communication Disorders (U01 - Clinical Trial Required)
Award Agency Discretion

The NIDCD is committed to identifying effective interventions for the treatment or prevention of communication disorders by suppor...

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SEC_ID: PAR-25-337 01/07/2028
Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Optional)
Award $499,000

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to stimulate efforts to translate s...

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SEC_ID: PAR-25-377 01/07/2027
Unveiling Health and Healthcare Disparities in Non-Communicable and Chronic Diseases in Latin America: Setting the Stage for Better Health Outcomes Across the Hemisphere (R01 - Clinical Trials Not Allowed)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) will support innovative, collaborative, and multi-disciplinary research focused on clini...

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SEC_ID: PAR-25-194 09/28/2027
Limited Competition: Ruth L. Kirschstein National Research Service Award (NRSA) Predoctoral Research Training Grant for the Clinical and Translational Science Awards (CTSA) Program (T32 Clinical Trial Not Allowed)
Award Agency Discretion

The National Center for Advancing Translational Sciences (NCATS) will award Ruth L. Kirschstein National Research Service Award (N...

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SEC_ID: PAR-25-197 05/28/2027
Limited Competition: NCATS Clinical and Translational Science Award (CTSA) Program Research Education Grants Programs (R25 - Clinical Trial Not Allowed)
Award Agency Discretion

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching g...

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SEC_ID: PAR-25-299 01/07/2028
Interventions to Address Disparities in Liver Diseases and Liver Cancer (R01 - Clinical Trials Optional)
Award Agency Discretion

This initiative will support multi-level and/or multi-domain intervention research to reduce disparities in liver diseases and liv...

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SEC_ID: PAR-25-325 09/10/2027
Integrating Biospecimen Science Approaches into Clinical Assay Development (U01 Clinical Trial Not Allowed)
Award Agency Discretion

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to support extramural research to i...

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SEC_ID: PAR-25-321 01/07/2028
Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Optional)
Award Agency Discretion

Through this engineering-oriented Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to encourage s...

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SEC_ID: PAR-25-154 07/16/2026
HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed)
Award $100,000

The purpose of this notice of funding opportunity (NOFO) is to solicit applications for pilot projects to identify new druggable t...

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SEC_ID: PAR-25-250 01/07/2028
NIDCD Research Dissertation Fellowship for Au.D. Audiologists (F32)
Award Agency Discretion

The purpose of the NIDCD Research Dissertation Fellowship for Au.D. Audiologists (F32) program is to support a comprehensive, rigo...

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SEC_ID: PAR-25-358 01/07/2028
NEI Clinical Research Study Planning Grant Program (R34 Clinical Trial Not Allowed)
Award $150,000

The NEI supports large-scale clinical vision research projects, including randomized clinical trials and epidemiologic studies on ...

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SEC_ID: PAR-25-296 10/19/2027
Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional)
Award $650,000

The CTSA Collaborative and Innovative Acceleration Award (CCIA) aims to accelerate the pace of translational research by supportin...

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SEC_ID: PAR-25-141 03/04/2027
NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
Award Agency Discretion

This NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) PAR, a re-issue of PAR-24-208, wa...

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SEC_ID: PAR-25-342 05/07/2027
Interventions on Health and Healthcare Disparities on Non-Communicable and Chronic Diseases in Latin America: Improving Health Outcomes Across the Hemisphere (R01 - Clinical Trial Required)
Award Agency Discretion

The purpose of this Notice of Funding Opportunity (NOFO) is to support innovative and interdisciplinary research teams focused on ...

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SEC_ID: PA-25-280 05/07/2028
Ruth L. Kirschstein National Research Service Award (NRSA) Short-Term Institutional Research Training Grant (Parent T35)
Award Agency Discretion

The National Institutes of Health (NIH) will award Ruth L. Kirschstein National Research Service Award (NRSA) Short-Term Instituti...

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SEC_ID: RFA-AT-25-003 11/23/2026
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)
Award $375,000

The purpose of this initiative is to: (1) support the efforts by R15-eligible Principal Investigators (PIs) to conduct rigorous ba...

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SEC_ID: PAR-25-353 10/25/2027
National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U19 Clinical Trial Optional)
Award Agency Discretion

Reissue of PAR-20-119. This FOA encourages applications to advance the discovery, preclinical development, and proof of concept (P...

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SEC_ID: RFA-HG-25-009 02/26/2027
Supporting Talented Early Career Researchers in Genomics (R01 Clinical Trial Optional)
Award Agency Discretion

This Funding Opportunity Announcement is intended to identify and support research projects by exceptionally promising Early Stage...

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SEC_ID: PAR-24-330 09/07/2027
Interventions to Reduce Sleep Health Disparities (R01 - Clinical Trials Optional)
Award Agency Discretion

This PAR is being reissued in accordance with the simplified review criteria in effect for application due dates after January 25,...

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SEC_ID: PAR-25-357 10/16/2027
NEI Research Grant for Vision-Related Secondary Data Analysis (R21 Clinical Trial Not Allowed)
Award Agency Discretion

The goal of this funding opportunity announcement (FOA) is to fund meritorious vision-related research projects that involve secon...

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SEC_ID: RFA-DC-25-002 10/12/2027
NIDCD Research Grants for Translating Basic Research into Clinical Practice (R01 Clinical Trial Optional)
Award $500,000

This Funding Opportunity Announcement (FOA) is intended to provide an avenue for basic scientists, clinicians and clinical scienti...

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SEC_ID: PAR-25-346 01/07/2028
Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed)
Award Agency Discretion

Through this engineering-oriented Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to encourage s...

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SEC_ID: RFA-TR-25-002 06/02/2026
Preclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed)
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This notice of funding opportunity (NOFO) provides funding to conduct efficacy studies in an established rare disease preclinical ...

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SEC_ID: PAR-24-280 11/02/2026
Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed)
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This Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed) PAR, wa...

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SEC_ID: PAR-25-032 01/07/2027
NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)
Award Agency Discretion

This Notice of Funding Opportunity Announcement (NOFO) intends to supports studies that are both necessary and sufficient to infor...

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SEC_ID: PAR-25-327 10/08/2027
Translational Efforts to Advance Gene-based Therapies for Ultra-Rare Neurological and Neuromuscular Disorders (U01 - Clinical Trial Optional)
Award Agency Discretion

The Ultra-Rare Gene-Based Therapy (URGenT) network supports Investigational New Drug (IND)-enabling studies and planning activitie...

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SEC_ID: PA-25-301 01/07/2028
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
Award Agency Discretion

The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests ...

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SEC_ID: PAR-25-374 05/07/2028
Translational Bioinformatics and Experimental Approaches to Advance Drug Repositioning and Combination Therapy Development for Alzheimers Disease and Related Dementias (R01 Clinical Trial Not Allowed)
Award $1,000,000

This Notice of Funding Opportunity (NOFO) invites applications that propose to use mouse models to conduct rigorous preclinical te...

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SEC_ID: PAR-25-352 10/25/2027
National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U01 Clinical Trial Optional)
Award Agency Discretion

Reissue of PAR-20-118. This Notice of Funding Opportunity (NOFO) encourages applications to advance the discovery, preclinical dev...

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SEC_ID: PAR-25-324 09/07/2028
Method to Extend Research in Time (MERIT) Award Extension Request (Type 4 eSubmission Clinical Trial Optional)
Award Agency Discretion

The National Cancer Institute (NCI) Method to Extend Research in Time (MERIT) (R37) Award provides extended grant support to Early...

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SEC_ID: RFA-EY-25-001 06/15/2026
BRAIN Initiative: New Concepts and Early-Stage Research for Recording and Modulation in the Nervous System (R21) (Clinical Trial Not Allowed)
Award $200,000

A central goal of the BRAIN Initiative is to understand how electrical and chemical signals code information in neural circuits an...

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SEC_ID: PAR-25-283 01/07/2028
Innovative Mental Health Services Research Not Involving Clinical Trials (R01 Clinical Trials Not Allowed)
Award Agency Discretion

The purpose of this Notice of Funding Announcement (NOFO) is to encourage innovative research that will inform and support the del...

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SEC_ID: PAR-25-100 05/07/2027
Pilot Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R34 Clinical Trial Optional)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) encourages pilot and preliminary research in preparation for larger-scale services resea...

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SEC_ID: PA-25-305 01/07/2028
NIH Research Project Grant (Parent R01 Clinical Trial Required)
Award Agency Discretion

The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests ...

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SEC_ID: PAR-24-279 11/02/2026
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required)
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This Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required) PAR, a re-...

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SEC_ID: RFA-DC-25-003 10/01/2026
Cooperative Agreement for In Vivo High-Resolution Imaging for Inner Ear Visualization (U01 Clinical Trial Required)
Award $500,000

This funding opportunity aims to support high risk clinical trials for the development of in vivo high-resolution structural and f...

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SEC_ID: RFA-DC-25-005 10/01/2026
In Vivo High-Resolution Imaging for Inner Ear Visualization (R01 Clinical Trial optional)
Award $500,000

This funding opportunity aims to support the development of in vivo high-resolution structural and functional imaging technologies...

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SEC_ID: PAR-25-313 10/14/2027
NCI Pathway to Independence Award (K99/R00 Clinical Trial Required)
Award Agency Discretion

The purpose of the NCI Pathway to Independence Award (K99/R00) program is to facilitate a timely transition of talented postdoctor...

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SEC_ID: PAR-25-284 01/07/2028
Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed)
Award $225,000

The purpose of this Notice of Funding Announcement (NOFO) is to encourage pilot research that is not an immediate precursor to tes...

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SEC_ID: PAR-25-338 01/07/2028
Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Not Allowed)
Award $499,000

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to stimulate efforts to translate s...

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SEC_ID: PAR-24-259 09/25/2026
Modern Equipment for Shared-use Biomedical Research Facilities: Advancing Research-Related Operations (S15 Clinical Trial Not Allowed)
Award $350,000

This Notice of Funding Opportunity (NOFO) invites eligible academic or research institutions to apply for funding support to purch...

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SEC_ID: PAR-24-296 12/03/2026
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)
Award Agency Discretion

This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leadi...

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SEC_ID: PAR-25-292 01/07/2028
The Role of Work in Health Disparities in the U.S. (R01 Clinical Trials Optional)
Award Agency Discretion

The purpose of this Notice of Funding Opportunity (NOFO) is to support innovative population-based research that can contribute to...

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SEC_ID: PAR-25-290 01/07/2028
Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R01 Clinical Trial Optional)
Award Agency Discretion

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage applications to pursue invasive neural recording studies ...

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SEC_ID: PAR-24-265 06/01/2027
Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)
Award Agency Discretion

The Shared Instrument Grant (SIG) Program encourages applications from groups of NIH-supported investigators to purchase or upgrad...

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SEC_ID: PAR-25-269 11/13/2026
NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33 Clinical Trial Required)
Award $350,000

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natu...

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SEC_ID: PAR-25-158 11/17/2026
Prevention and Intervention Approaches for Fetal Alcohol Spectrum Disorders (R61/R33 Clinical Trial Optional)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) focuses on prevention and intervention strategies for fetal alcohol spectrum disorders (...

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SEC_ID: PAR-24-174 08/06/2026
Global Infectious Disease Research Training Program (D43 Clinical Trial Optional)
Award Agency Discretion

This Funding Opportunity Announcement (FOA) encourages joint applications for the Global Infectious Disease (GID) Research Trainin...

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SEC_ID: RFA-HL-26-020 12/23/2027
Catalyze: Product Definition Medical Device Prototype Optimization (R33 - Clinical Trial Not Allowed)
Award Agency Discretion

The goal of the NHLBI Catalyze Program is to provide a comprehensive suite of support and services to facilitate the transition of...

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SEC_ID: PAR-25-077 10/16/2026
CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Basic Research on Chemical Threats that Affect the Nervous System (R01 Clinical Trial Not Allowed)
Award $300,000

This announcement invites applications for basic research projects on chemical warfare agents, toxic industrial chemicals, and pes...

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SEC_ID: PAR-25-057 01/06/2028
NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
Award Agency Discretion

To support UG3/UH3 phased, cooperative agreement research applications to plan and implement clinical trials within the mission of...

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SEC_ID: PAR-25-442 02/17/2028
Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications for exploratory and early-stage projects that ...

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SEC_ID: RFA-DA-26-034 11/18/2027
Chemical Countermeasures Research Program (CCRP) Initiative: Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids (R01 Clinical Trial Not Allowed)
Award $300,000

This notice of funding opportunity (NOFO) will support research towards understanding and mitigating the deleterious effects of ac...

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SEC_ID: PA-25-304 01/07/2028
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)
Award Agency Discretion

The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the earl...

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SEC_ID: RFA-AG-26-011 05/26/2027
NIA Expanding Research in AD/ADRD (ERA) Summer Research Education Program (R25 Independent Clinical Trial Not Allowed)
Award $200,000

This Notice of Funding Opportunity (NOFO) invites R25 applications to support the development and implementation of summer researc...

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SEC_ID: RFA-AG-26-010 05/26/2027
NIA Expanding Research in AD/ADRD (ERA) Postbaccalaureate Research Education Program (R25 Independent Clinical Trial Not Allowed)
Award $400,000

This Notice of Funding Opportunity Announcement (NOFO) invites R25 applications to support the development and implementation of r...

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SEC_ID: PA-25-306 01/07/2028
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)
Award Agency Discretion

The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the earl...

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SEC_ID: RFA-ES-25-002 04/20/2027
Environmental Health Sciences Core Centers Program (P30 Clinical Trials Optional)
Award Agency Discretion

This Notice of Funding Opportunity Announcement (NOFO) invites grant applications for Environmental Health Sciences Core Centers (...

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SEC_ID: PAR-23-126 09/25/2026
Limited Competition: National Primate Research Centers (P51) (Clinical Trials Not Allowed)
Award Agency Discretion

This funding opportunity announcement (FOA) encourages grant applications that support the activities of the National Primate Rese...

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SEC_ID: PAR-25-446 08/21/2028
Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)
Award $3,000,000

The purpose of this Funding Opportunity (NOFO) is to solicit grant applications to support research on the discovery and developme...

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SEC_ID: PAR-25-195 09/28/2027
Limited Competition: Ruth L. Kirschstein National Research Service Award (NRSA) Postdoctoral Research Training Grant for the Clinical and Translational Science Awards (CTSA) Program (T32 Clinical Trial Not Allowed)
Award Agency Discretion

The National Center for Advancing Translational Sciences (NCATS) will award Ruth L. Kirschstein National Research Service Award (N...

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SEC_ID: PA-25-080 09/07/2027
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of the NIH Research Conference Grant (R13) is to support high quality conferences that are relevant to the public heal...

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SEC_ID: PA-24-190 05/07/2027
Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Required)
Award Agency Discretion

The purpose of the Mentored Quantitative Research Career Development Award (K25) is to attract to NIH-relevant research those inve...

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SEC_ID: PAR-24-143 05/07/2027
NIDCD Research Career Enhancement Award for Established Investigators (K18 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of the NIDCD Research Career Enhancement Award for Established Investigators (K18) program is to enable established, p...

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SEC_ID: PAR-24-200 07/14/2026
NINDS Research Education Opportunities (R25 Clinical Trial Not Allowed)
Award Agency Discretion

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching ...

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SEC_ID: PAR-23-204 05/25/2026
NEI Collaborative Clinical Vision Research Project: Coordinating Center Grant (UG1 Clinical Trial Required)
Award Agency Discretion

The NEI uses UG1 cooperative agreement awards to support investigator-initiated large-scale clinical trials, human gene-transfer, ...

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SEC_ID: PAR-24-167 09/25/2026
Utilizing Equipment to Study Environmental Extrinsic Factors and Enhance Rigor and Reproducibility of Animal Research (R24, Clinical Trials Not-Allowed)
Award Agency Discretion

The Office of Research Infrastructure Programs (ORIP) invites grant applications from core facilities, resource centers, animal vi...

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SEC_ID: PA-24-185 05/07/2027
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of the NIH Mentored Patient-Oriented Research Career Development Award (K23) is to support the career development of i...

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SEC_ID: PAR-24-140 05/07/2027
NIDCD Research Career Enhancement Award for Established Investigators (K18 Clinical Trial Required)
Award Agency Discretion

The purpose of the NIDCD Research Career Enhancement Award for Established Investigators (K18) program is to enable established, p...

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SEC_ID: PA-24-201 04/18/2027
Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)
Award Agency Discretion

The National Institutes of Health (NIH) hereby notify the applicant community that funds may be available for applications based o...

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SEC_ID: PA-24-187 05/07/2027
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Required)
Award Agency Discretion

The purpose of the NIH Midcareer Investigator Award in Patient-Oriented Research (K24) is to provide support to mid-career health-...

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SEC_ID: PA-24-188 05/07/2027
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of the NIH Midcareer Investigator Award in Patient-Oriented Research (K24) is to provide support to mid-career health-...

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SEC_ID: RFA-OD-24-013 05/28/2026
Building Interdisciplinary Research Careers in Women's Health (BIRCWH) (K12 Clinical Trial Optional)
Award $840,000

The NIH Office of Research on Women's Health (ORWH) and participating NIH Institutes and Centers invite institutional career devel...

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SEC_ID: PAR-24-027 10/30/2026
Population Assessment of Tobacco and Health (PATH) Study Biospecimen Access (X01)
Award Agency Discretion

The Population Assessment of Tobacco and Health (PATH) Study provides the scientific community with biospecimens (urine, plasma, s...

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SEC_ID: PAR-24-089 11/13/2026
NIDA Mentored Clinical Scientist Development Program Award in Substance Use and Substance Use Disorder Research (K12 Clinical Trial Optional)
Award $750,000

This funding opportunity announcement (FOA) encourages applications for institutional research career development (K12) programs t...

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SEC_ID: PAR-23-240 05/25/2026
Alcohol and Other Substance Use Research Education Programs for Health Professionals (R25 Clinical Trial Not Allowed)
Award $250,000

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching ...

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SEC_ID: PAR-23-286 10/14/2026
NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of the NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00) program is to increase and...

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SEC_ID: PAR-23-278 01/07/2027
Cancer Research Education Grants Program - Curriculum or Methods Development (R25 Clinical Trial Not Allowed)
Award $150,000

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching ...

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SEC_ID: PA-23-317 11/24/2026
Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)
Award Agency Discretion

The National Institutes of Health (NIH) hereby notifies NIH award recipients that funds may be available for revision applications...

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SEC_ID: PAR-23-166 08/07/2026
Native American Research Centers for Health (NARCH) (S06 Clinical Trial Optional)
Award Agency Discretion

The purpose of theNative American Research Centers for Health (NARCH) program is to fund federally-recognized American Indian/Alas...

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SEC_ID: PAR-23-201 05/25/2026
NEI Collaborative Clinical Vision Research Project: Resource Center Grant (UG1 Clinical Trial Required)
Award Agency Discretion

The NEI uses UG1 cooperative agreement awards to support investigator-initiated large-scale clinical trials, human gene-transfer, ...

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SEC_ID: PAR-23-209 05/25/2026
NEI Collaborative Clinical Vision Research: Chair's Grant (UG1-Clinical Trial Required)
Award Agency Discretion

The NEI uses UG1 cooperative agreement awards to support investigator-initiated large-scale clinical trials, human gene-transfer, ...

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SEC_ID: PAR-23-184 07/08/2026
Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01 Clinical Trial Not Allowed)
Award Agency Discretion

The Center for Inherited Disease Research (CIDR) high-throughput genotyping, sequencing and supporting statistical genetics servic...

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SEC_ID: RFA-HL-26-002 04/28/2027
NHLBI Outstanding Investigator Award (OIA) (R35 Clinical Trial Optional)
Award Agency Discretion

The purpose of the NHLBI Outstanding Investigator Award (OIA) is to promote scientific productivity and innovation by providing lo...

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SEC_ID: RFA-HL-26-003 04/28/2027
NHLBI Emerging Investigator Award (EIA) (R35 Clinical Trial Optional)
Award Agency Discretion

The purpose of the NHLBI Emerging Investigator Award (EIA) is to promote scientific productivity and innovation by providing long-...

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SEC_ID: PAR-24-149 05/07/2027
NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01 Clinical Trial Required)
Award Agency Discretion

The purpose of the NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01) is to support comprehe...

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SEC_ID: PA-24-178 05/07/2027
Independent Scientist Award (Parent K02 - Independent Clinical Trial Required)
Award Agency Discretion

The purpose of the NIH Independent Scientist Award (K02) is to foster the development of outstanding scientists and enable them to...

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SEC_ID: PAR-24-159 05/07/2027
NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01 Independent Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of the NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01) is to support comprehe...

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SEC_ID: PA-24-179 05/07/2027
Independent Scientist Award (Parent K02 - Independent Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of the NIH Independent Scientist Award (K02) is to foster the development of outstanding scientists and enable them to...

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SEC_ID: PA-24-194 05/07/2027
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of the NIH Pathway to Independence Award (K99/R00) program is to increase and maintain a strong cohort of new and tale...

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SEC_ID: PAR-24-214 01/07/2027
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)
Award $375,000

The purpose of this Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions is to support small scale re...

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SEC_ID: PAR-24-210 05/18/2026
Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Centers (P50 Clinical Trial Optional)
Award $1,500,000

This Funding Opportunity Announcement (FOA) invites applications for centers to support transdisciplinary teams of clinical and me...

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SEC_ID: PAS-25-236 09/07/2027
D-START: Data Science Track Award for Research Transition (D/START) (R03-Clinical Trial Optional)
Award $100,000

Data science is an important cross-cutting research approach in the 2022 - 2026 NIDA Strategic Plan and increasing the capacity of...

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SEC_ID: PAR-25-074 10/14/2026
Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH2/UH3 Clinical Trial Not Allowed)
Award Agency Discretion

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications to support the validat...

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SEC_ID: PA-24-176 05/07/2027
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of the NIH Mentored Research Scientist Development Award (K01) is to provide support and protected time (three to five...

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SEC_ID: PAR-25-064 09/07/2026
Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R21 Clinical Trial Optional)
Award Agency Discretion

The goal of this Funding Opportunity Announcement (FOA) is to encourage applications for studies that will enhance knowledge of me...

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SEC_ID: PAR-24-273 01/07/2028
Advancing Healthcare for Older Adults from Populations that Experience Health Disparities (R01 - Clinical Trial Optional)
Award Agency Discretion

The purpose of this initiative is to advance the science and implementation of innovative multi-level health care research for old...

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SEC_ID: PAR-25-055 06/22/2026
Clinical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders (U01 Clinical Trial Optional)
Award Agency Discretion

The purpose of this Program Announcement (PAR) is to enable clinical validation of strong candidate biomarkers for neurological di...

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SEC_ID: PAR-25-287 01/07/2028
Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R01 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage applications seeking to develop the next generation of br...

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SEC_ID: PAR-25-206 01/07/2028
Pilot Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)
Award Agency Discretion

NIMH seeks applications for pilot effectiveness projects to evaluate the preliminary effectiveness of therapeutic and service deli...

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SEC_ID: PAR-25-059 10/20/2027
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Neurotherapeutic Agent Identification (R61/R33 Clinical Trial Not Allowed)
Award $750,000

This funding opportunity announcement (FOA) encourages research grant applications to develop in vitro and/or ex vivo assays and c...

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SEC_ID: PAR-25-096 09/07/2026
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)
Award $200,000

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) along with other participating Institutes e...

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SEC_ID: PAS-25-205 01/06/2028
Stimulating Hematology Investigation: New Endeavors (SHINE) (R01 Clinical Trial Not Allowed)
Award Agency Discretion

The Stimulating Hematology Investigation: New Endeavors (SHINE) program is intended to promote innovative, high-quality nonmaligna...

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SEC_ID: RFA-HL-26-016 12/23/2027
Catalyze: Enabling Technologies and Transformative Platforms for HLBS Research (R33 - Clinical Trials Not Allowed)
Award $350,000

The goal of the NHLBI Catalyze Program is to provide a comprehensive suite of support and services to facilitate the transition of...

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SEC_ID: RFA-HG-24-026 08/02/2026
Limited Competition: Building Partnerships and Broadening Perspectives to Advance Ethical, Legal, and Social Implications (ELSI) Research (BBAER) Program (UM1), Clinical Trial Optional
Award $850,000

The National Human Genome Research Institute (NHGRI) seeks to broaden the types of knowledge, skills, expertise, experience, and p...

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SEC_ID: PAR-25-226 11/19/2026
Seamless Early-Stage Clinical Drug Development (Phase 1 to 2a) for Novel therapeutic Agents for the Spectrum of Alzheimer's Disease (AD) and AD-related Dementias (ADRD) (UG3/UH3 Clinical Trial Required)
Award Agency Discretion

The purpose of this Notice of Funding Opportunity (NOFO) is to invite applications that bundle independent protocols for phase 1 c...

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SEC_ID: PAR-24-260 01/27/2027
Tribal Institutional Review Board Establishment and Enhancement (TIRBEE) (R24 - Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of the Tribal Institutional Review Board Establishment and Enhancement (TIRBEE) award is to support federally recogniz...

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SEC_ID: PAR-25-180 10/15/2027
First in Human and Early Stage Clinical Trials of Novel Investigational Drugs or Neuromodulatory Device-based Interventions for Psychiatric Disorders (U01 Clinical Trial Required)
Award Agency Discretion

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage cooperative agreement applications to support early stage...

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SEC_ID: PAR-25-244 11/16/2027
Basic Research in Cancer Health Disparities (R21 Clinical Trial Not Allowed)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) encourages grant applications from investigators interested in conducting basic, mechani...

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SEC_ID: PAR-25-062 01/06/2028
Continuation or Revision of NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UH3 Clinical Trial Required)
Award Agency Discretion

To support competing renewal or competitive revision of ongoing clinical trials supported by the National Institute of Dental and ...

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SEC_ID: PAR-25-184 10/15/2027
Early Stage Testing of Pharmacologic or Neuromodulatory Device-based Interventions for the Treatment of Mental Disorders (R61/R33 Clinical Trial Required)
Award Agency Discretion

NIMH requires an experimental therapeutics approach for the development and testing of therapeutic interventions, in which studies...

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SEC_ID: PAR-25-193 09/07/2026
Alcohol Treatment, Pharmacotherapy, and Recovery Research (R34 Clinical Trial required)
Award Agency Discretion

The National Institute on Alcohol Abuse and Alcoholism solicits applications for an R34 Clinical Trial Optional mechanism focusing...

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SEC_ID: PAR-24-304 10/14/2026
Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants (R01 Clinical Trial Not Allowed)
Award Agency Discretion

Through this Notice of Funding Opportunity (NOFO) is to accelerate the pace of translation of NCI-supported methods/assays/technol...

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SEC_ID: PAR-25-039 09/07/2026
Schizophrenia and related disorders during mid- to late-life (R01 Clinical Trial Optional)
Award Agency Discretion

Although the majority living with schizophrenia and related disorders are over 35 years old, including those first diagnosed and t...

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SEC_ID: RFA-MH-26-120 06/15/2027
BRAIN Initiative: Reagent Resources for Brain Cell Type-Specific Access to Broaden Distribution of Enabling Technologies for Neuroscience (U24 Clinical Trial Not Allowed)
Award Agency Discretion

This Notice of Funding Opportunity Announcement (NOFO) from the NIH Brain Research through Advancing Innovative Neurotechnologies ...

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SEC_ID: PAR-25-067 09/07/2026
Social disconnection and Suicide Risk in Late Life (R01 Clinical Trial Optional)
Award Agency Discretion

This initiative seeks to solicit applications for research projects that address the link between social disconnection including b...

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SEC_ID: PAR-25-270 11/13/2026
NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)
Award $1,050,000

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natu...

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SEC_ID: PAR-25-060 10/20/2027
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed)
Award $750,000

This funding opportunity announcement (FOA) encourages the development and validation of animal models and human/animal tissue ex ...

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SEC_ID: PAR-25-037 09/07/2026
Cellular and Molecular Biology of Complex Brain Disorders (R21 Clinical Trial Not Allowed)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) encourages research on the biology of high confidence risk factors associated with compl...

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SEC_ID: RFA-DA-26-055 12/03/2027
Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of this Notice of Opportunity Announcement (NOFO) is to invite applications proposing the innovative analysis of exist...

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SEC_ID: PAR-25-079 01/07/2027
Academic-Industrial Partnerships (AIP) to Translate and Validate In Vivo Imaging Systems (R01 Clinical Trial Optional)
Award $500,000

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to stimulate translation of scienti...

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SEC_ID: PAR-24-250 06/10/2026
Standardizing Data and Metadata from Wearable Devices (R01 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of this NOFO is to support the creation of standards and related efforts that will allow researchers to easily access ...

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SEC_ID: RFA-DA-26-056 12/03/2027
Accelerating the Pace of Substance Use Research Using Existing Data (R21 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of this notice of funding opportunity (NOFO) is to invite applications proposing the innovative analysis of existing s...

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SEC_ID: PAR-25-235 01/07/2027
Personal Health Informatics for Delivering Actionable Insights to Individuals (R01 Clinical Trial Optional)
Award $250,000

The purpose of this Notice of Funding Opportunity (NOFO) is to advance the development of novel informatics and data science appro...

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SEC_ID: PAR-25-120 10/15/2027
NIDCD Early Career Research(ECR) Award (R21 Clinical Trial Optional)
Award Agency Discretion

The NIDCD Early Career Research (ECR) Award (R21) is intended to support both basic and clinical research from scientists who are ...

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SEC_ID: RFA-NS-24-031 01/28/2027
BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)
Award $750,000

Awarded activities will facilitate the translation of novel recording and modulation technologies that can be used to treat and/or...

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SEC_ID: PAR-26-042 03/05/2029
Research Grants in Clinical Informatics (R01 Clinical Trial Optional)
Award $2,500,000

The National Library of Medicine (NLM) seeks applications for innovative research in clinical informatics. The overarching goal of...

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SEC_ID: PAR-26-040 03/05/2029
Advancing Bioinformatics, Translational Bioinformatics and Computational Biology Research (R01 Clinical Trial Optional)
Award $2,500,000

The National Library of Medicine (NLM) seeks applications for research projects that drive groundbreaking innovation and advanced ...

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SEC_ID: RFA-NS-25-017 06/16/2026
BRAIN Initiative: Optimization of Instrumentation and Device Technologies for Recording and Modulation in the Nervous System (U01 Clinical Trials Not Allowed)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) seeks applications to optimize instrumentation and device technologies for recording and...

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SEC_ID: RFA-NS-25-018 06/16/2026
BRAIN Initiative: New Technologies and Novel Approaches for Recording and Modulation in the Nervous System (R01 Clinical Trial Not Allowed)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) seeks applications for proof-of-concept testing and development of new technologies and ...

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SEC_ID: PAR-25-322 08/25/2028
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)
Award Agency Discretion

The Stephen I. Katz Early Stage Investigator Research Project Grant supports an innovative project that represents a change in res...

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SEC_ID: RFA-HL-26-012 01/10/2028
Stimulating Access to Research in Residency (StARR) (R38 Independent Clinical Trial Not Allowed)
Award Agency Discretion

The overall goal of the Stimulating Access to Research in Residency (StARR) program is to provide resident clinicians in training ...

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SEC_ID: PAR-25-441 07/07/2028
Native American Research Centers for Health (NARCH) Planning Grants (R34 - Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of the Native American Research Centers for Health (NARCH) Planning Grants program is to support federally recognized ...

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SEC_ID: RFA-DA-27-004 11/08/2027
BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain (R01 Clinical Trial Not Allowed)
Award Agency Discretion

The Theories, Models and Methods (TMM) initiative will support the development of computational tools for understanding dynamic br...

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SEC_ID: PAR-25-439 05/07/2028
Community-Partnered Nursing Research Centers (P20 Clinical Trial Optional)
Award $500,000

The purpose of this initiative is to support the development of innovative research centers to foster nursing-led programs that pr...

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SEC_ID: PAR-25-049 07/09/2026
NIH SIREN Neurologic Clinical Trials (UG3/UH3 - Clinical Trial Required)
Award Agency Discretion

This announcement (NOFO) encourages applications for multi-center clinical trials focused on neurological emergencies. Successful ...

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SEC_ID: PAR-25-124 01/07/2028
NCMRR Early Career Research Award (R03 Clinical Trial Optional)
Award $200,000

The National Center for Medical Rehabilitation Research (NCMRR) Early Career Research (ECR) Award (R03) is intended to support bot...

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SEC_ID: PAR-26-115 05/26/2028
Institutional Network Award for Promoting Kidney, Urologic, and Hematologic Research Training (U2C - Clinical Trial Not Allowed)
Award $4,000,000

Responding to the needs of the scientific community to bolster a vibrant and sustainable research workforce, the Division of Kidne...

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SEC_ID: PAR-26-121 05/26/2028
Maximizing Investigators' Research Award (MIRA) (R35 - Clinical Trial Optional)
Award Agency Discretion

The Maximizing Investigators' Research Award (MIRA) provides support for individual investigators for research within the scientif...

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SEC_ID: RFA-OD-25-010 09/28/2028
Resource-Related Research Projects for Development of Models and Related Materials for Studying Human Health and Diseases (R24 Clinical Trials Not Allowed)
Award $5,000,000

The Office of Research Infrastructure Programs (ORIP) encourages grant applications aimed at developing, characterizing, or improv...

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SEC_ID: PAR-26-033 09/25/2028
NIGMS Institutional Biomedical Undergraduate Research Training (BURT) Program (T34)
Award Agency Discretion

The goal of the Institutional Biomedical Undergraduate Research Training (BURT) program is to strengthen research training environ...

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SEC_ID: PAR-25-444 09/25/2028
Cancer Center Support Grants (CCSGs) for NCI-designated Cancer Centers (P30 Clinical Trial Optional)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) invites applications for P30 Cancer Center Support Grants (CCSGs) to support NCI-Designa...

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SEC_ID: PA-26-001 11/30/2028
Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)
Award Agency Discretion

Current recipients of specific types of NIH research grants may apply for administrative supplements, using this Notice of Funding...

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SEC_ID: RFA-DK-26-310 01/27/2027
Diabetes Research Centers (P30 Clinical Trial Optional)
Award $18,200,000

This Notice of Funding Opportunity (NOFO) invites applications for Diabetes Research Centers (DRCs) that are designed to support a...

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SEC_ID: PAR-26-116 03/06/2027
Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional)
Award $500,000

The goal of this program is to support collaborative translational research projects aligned with NIH efforts to enhance the trans...

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SEC_ID: RFA-DK-26-315 10/06/2026
Advancing Research on the Application of Digital Health Technology to the Management of Type 2 Diabetes (R01- Clinical Trail Required)
Award Agency Discretion

This notice of funding opportunity (NOFO) invites applications designed to examine the efficacy and clinical effectiveness of mult...

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SEC_ID: PAR-25-447 05/08/2028
NHLBI TOPMed: Omics Phenotypes of Heart, Lung, and Blood Disorders (X01 - Clinical Trial Not Allowed)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) invites applications to use NHLBI-funded TransOmics for Precision Medicine (TOPMed) prog...

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SEC_ID: PAR-25-450 07/20/2028
Clinical Trial Readiness for Rare Diseases, Disorders, and Syndromes (R21 Clinical Trial Not Allowed)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) invites researchers to submit applications for support of clinical projects that address...

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SEC_ID: PAR-25-449 06/07/2028
Mind and Body Interventions to Restore Whole Person Health via Emotional Well-Being Mechanisms (R61/R33 Clinical Trial Required)
Award Agency Discretion

The National Center for Complementary and Integrative Health (NCCIH) announces this Notice of Funding Opportunity (NOFO) to solici...

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SEC_ID: RFA-DC-26-001 06/17/2027
Early-Stage Dissemination and Implementation Research in Communication Disorders (R21 Clinical Trial Optional)
Award $1,000,000

The National Institute on Deafness and other Communication Disorders (NIDCD) intends to re-issue a Notice of Funding Opportunity (...

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SEC_ID: PAR-26-138 01/26/2027
National Centers for Cryo-electron Tomography (cryoET) (R24 -Clinical Trial Not Allowed)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) is for support of National Centers for Cryoelectron Tomography (CryoET) to provide natio...

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SEC_ID: RFA-NS-27-001 10/06/2028
BRAIN Initiative: Research Resource Grants for Technology Integration and Dissemination (U24 Clinical Trial Not Allowed)
Award $10,000,000

This notice of funding opportunity (NOFO) supports efforts to disseminate resources for integration into neuroscience research pra...

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SEC_ID: RFA-AI-27-019 06/04/2026
Impact of Initial Influenza Exposure on Immunity in Infants (U01 Clinical Trial Not Allowed)
Award $9,600,000

The purpose of this notice of funding opportunity (NOFO) is to support the establishment or continuation of longitudinal infant co...

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SEC_ID: PA-26-002 05/07/2029
NIH Collaborative International Research Project (Parent PF5 Clinical Trial Optional)
Award Agency Discretion

The National Institutes of Health (NIH) seeks to advance its mission by maintaining strong, productive, and secure international r...

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SEC_ID: RFA-OD-23-001 05/09/2026
Animal and Biological Material Resource Centers (P40) (Clinical Trials Not-Allowed)
Award Agency Discretion

This FOA encourages grant applications for Animal and Biological Material Resource Centers. These Centers provide support for spec...

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SEC_ID: PA-24-182 05/08/2027
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)
Award Agency Discretion

The primary purpose of the NIH Mentored Clinical Scientist Research Career Development Awards (K08) program is to prepare qualifie...

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SEC_ID: PA-24-181 05/08/2027
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required)
Award Agency Discretion

The primary purpose of the NIH Mentored Clinical Scientist Research Career Development Awards (K08) program is to prepare qualifie...

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SEC_ID: PA-24-184 05/08/2027
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)
Award Agency Discretion

The purpose of the NIH Mentored Patient-Oriented Research Career Development Award (K23) is to support the career development of i...

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SEC_ID: RFA-RM-26-017 06/23/2026
Pilot Projects Enhancing Utility and Usage of Common Fund Data Sets (R03 Clinical Trial Not Allowed)
Award $4,000,000

Many valuable and widely available data sets have been generated by multiple Common Fund programs. The purpose of this NOFO is to ...

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SEC_ID: PAR-26-134 11/22/2028
The Metastasis Research Network (MetNet): MetNet Research Projects (U01 Clinical Trial Not Allowed)
Award $500,000

The National Cancer Institute's (NCI) Metastasis Research Network (MetNet) is a collection of U54 Research Centers that support us...

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SEC_ID: RFA-DA-25-060 03/05/2027
High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional)
Award $1,500,000

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of HIV and sub...

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SEC_ID: RFA-DA-25-024 03/06/2027
High Priority HIV and Substance Use Research (R01 Clinical Trial Optional)
Award Agency Discretion

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of HIV and sub...

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SEC_ID: PAR-25-362 11/05/2028
Early Immune System Development and Ontogeny (R01 Clinical Trial Optional)
Award $400,000

The purpose of this Notice of Funding Opportunity (NOFO) is tofurther elucidate the mechanisms of early immune development in uter...

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SEC_ID: PAR-25-318 11/16/2027
Advancing HIV/AIDS Research within the Mission of the NIDCD (R21 Clinical Trial Optional)
Award Agency Discretion

The purpose of this Notice of Funding Opportunity (NOFO) is to stimulate HIV/AIDS research within the scientific mission areas of ...

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SEC_ID: PAR-25-319 11/05/2027
Advancing HIV/AIDS Research within the Mission of the NIDCD (R01 Clinical Trial Optional)
Award Agency Discretion

The purpose of this Funding Opportunity Announcement (FOA) is to stimulate HIV/AIDS research within the scientific mission areas o...

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SEC_ID: PAS-25-073 11/05/2027
Priority HIV/AIDS Research within the Mission of NIDDK (R01 Clinical Trial Optional)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) seeks to stimulate HIV/AIDS research within the mission of the National Institute of Dia...

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SEC_ID: PAR-25-068 11/16/2027
Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of NIDDK (R21 Clinical Trial Not Allowed)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) invites applications for innovative basic and translational pilot research projects with...

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SEC_ID: PAR-24-329 03/16/2027
Development and Testing of Novel Interventions to Improve HIV Prevention, Treatment, and Program Implementation for People Who Use Substances (R34 Clinical Trial Required)
Award Agency Discretion

This notice of funding opportunity (NOFO) encourages formative research, intervention development, and pilot-testing of interventi...

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SEC_ID: PAR-27-013 11/02/2028
Data Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative U24 Clinical Trial Required)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) supports applications for a collaborating Data Coordinating Center (DCC) for investigato...

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SEC_ID: PAR-27-012 11/02/2028
Clinical Coordinating Center for Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) supports applications to develop and conduct a Clinical Coordinating Center (CCC) for in...

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SEC_ID: PAR-27-011 11/02/2028
Single-Site Investigator-Initiated Clinical Trials (R61/R33 Clinical Trial Required)
Award Agency Discretion

This Notice of Funding Opportunity (NOFO) supports applications to develop and conduct investigator-initiated single site clinical...

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SEC_ID: PAR-24-233 05/25/2026
NIMH Research Education Mentoring Program for HIV Researchers (R25 Clinical Trial Not Allowed)
Award $200,000

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching ...

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SEC_ID: PAR-24-164 05/25/2026
Developmental AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional)
Award Agency Discretion

The National Institute of Mental Health (NIMH) Division of AIDS Research (DAR) encourages applications for Center Core grants (P30...

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SEC_ID: PAR-24-165 05/25/2026
AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional)
Award Agency Discretion

The National Institute of Mental Health (NIMH) Division of AIDS Research (DAR) encourages applications for Center Core grants (P30...

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SEC_ID: PAR-24-129 09/25/2026
Limited Competition: Specific Pathogen Free Macaque Colonies to Support HIV/AIDS Research (U42 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of this Notice of Funding Opportunity (NOFO) is to provide continuing support for specific pathogen-free (SPF) macaque...

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SEC_ID: PAR-26-106 01/25/2028
Development of Collaborative Research Facilities or Research-Resource Facilities (C06 Clinical Trial Not Allowed)
Award $88,000,000

This Notice of Funding Opportunity (NOFO) solicits applications to develop shared-use research facilities or research-supporting f...

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SEC_ID: PA-24-183 05/24/2026
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Basic Experimental Studies with Humans Required)
Award Agency Discretion

The primary purpose of the NIH Mentored Clinical Scientist Research Career Development Awards (K08) program is to prepare qualifie...

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SEC_ID: PAR-23-288 05/24/2026
NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 - Independent Basic Experimental Studies with Humans Required)
Award Agency Discretion

The purpose of the NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00) program is to increase and...

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SEC_ID: PA-24-192 05/24/2026
Mentored Quantitative Research Development Award (Parent K25 Independent Basic Experimental Studies with Humans Required)
Award Agency Discretion

The purpose of the Mentored Quantitative Research Career Development Award (K25) is to attract to NIH-relevant research those inve...

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SEC_ID: PA-24-186 05/24/2026
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Basic Experimental Studies with Humans Required)
Award Agency Discretion

The purpose of the NIH Mentored Patient-Oriented Research Career Development Award (K23) is to support the career development of i...

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SEC_ID: PAR-24-150 05/24/2026
NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01 Independent Basic Experimental Studies with Humans Required)
Award Agency Discretion

The purpose of the NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01) is to support comprehe...

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SEC_ID: PAR-24-142 05/24/2026
NIDCD Research Career Enhancement Award for Established Investigators (K18 Independent Basic Experimental Studies with Humans Required)
Award Agency Discretion

The purpose of the NIDCD Research Career Enhancement Award for Established Investigators (K18) program is to enable established, p...

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SEC_ID: PAR-25-445 10/03/2026
NIDCD Clinical Research Center Grant (P50 Clinical Trial Optional)
Award Agency Discretion

The National Institute on Deafness and Other Communication Disorders (NIDCD) invites applications for Clinical Research Center Gra...

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SEC_ID: PAR-24-128 01/25/2027
Medical Scientist Training Program (MSTP) (T32)
Award Agency Discretion

The goal of the Medical Scientist Training Program (MSTP) is to develop a broad pool of highly trained physician-scientist leaders...

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SEC_ID: RFA-OD-25-011 09/26/2028
Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed)
Award $1,300,000

This Notice of Funding Opportunity (NOFO) encourages grant applications for Animal and Biological Material Resource Centers. These...

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SEC_ID: RFA-NS-26-001 11/10/2026
Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)
Award $40,000,000

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications for the conduct of scientific research utilizi...

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SEC_ID: RFA-AI-27-012 07/09/2026
Coccidioidomycosis Collaborative Research Centers (P01 Clinical Trial Not Allowed)
Award $4,800,000

The purpose of the notice of funding opportunity (NOFO) is to solicit applications for a Coccidioidomycosis Collaborative Research...

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SEC_ID: RFA-AI-27-016 07/10/2026
Tuberculosis Research Advancement Centers (TRACs) (P30 Clinical Trial Not Allowed)
Award $4,000,000

The purpose of this notice of funding opportunity (NOFO) is to support applications for the Tuberculosis (TB) Research Advancement...

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SEC_ID: PAR-27-081 03/05/2027
Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed)
Award Agency Discretion

The purpose of this Notice of Funding Opportunity (NOFO) is to support investigators who have the interest and capability to join ...

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SEC_ID: PAR-27-075 11/05/2028
CCRP Initiative: Promoting a Basic Understanding of Chemical Threats to Skin (R01 Clinical Trial Not Allowed)
Award $300,000

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit basic research applications to investigate the pathological...

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SEC_ID: RFA-DE-27-002 07/10/2026
Accelerating Product Excellence in Innovation and for Clinical Adoption (APEx) (U24 Clinical Trial Not Allowed)
Award $6,000,000

This Notice of Funding Opportunity (NOFO) solicits cooperative agreement research applications to support a multidisciplinary prog...

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SEC_ID: RFA-DC-27-004 02/11/2027
BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Clinical Trial Not Allowed)
Award $6,000,000

Invasive surgical procedures in humans offer the unique opportunity to intracranially record and stimulate neuronal activity withi...

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SEC_ID: PAR-27-073 07/05/2029
Research Opportunities in Cancer Epidemiology Cohort Studies (U01 Clinical Trial Not Allowed)
Award Agency Discretion

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) encourages grant applications to support re...

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SEC_ID: PAR-27-072 07/05/2029
Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional)
Award $500,000

This Notice of Funding Opportunity (NOFO) encourages collaborations between the life and physical sciences that: 1) apply a multid...

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SEC_ID: PAR-27-077 05/25/2029
NIH Science Education Partnership Award (SEPA) (R25 - Clinical Trial Not Allowed)
Award Agency Discretion

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching g...

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SEC_ID: PA-25-303 05/24/2026
NIH Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required)
Award Agency Discretion

The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests ...

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SEC_ID: PA-25-307 05/24/2026
NIH Exploratory/Developmental Research Project Grant (Parent R21 Basic Experimental Studies with Humans Required)
Award Agency Discretion

The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the earl...

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SEC_ID: PA-24-189 05/24/2026
Midcareer Investigator Award in Patient-Oriented Research (Parent K24 - Independent Basic Experimental Studies with Humans Required)
Award Agency Discretion

The purpose of the NIH Midcareer Investigator Award in Patient-Oriented Research (K24) is to provide support to mid-career health-...

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SEC_ID: PA-25-126 05/24/2026
NICHD Small Research Grant Program (R03 Basic Experimental Studies with Humans Required)
Award $50,000

The NICHD Small Research Grant Program (R03Basic Experimental Studies with HumansRequired) supports clinical trials that fall with...

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SEC_ID: PA-24-180 05/24/2026
Independent Scientist Award (Parent K02 Independent Basic Experimental Studies with Humans Required)
Award Agency Discretion

The purpose of the NIH Independent Scientist Award (K02) is to foster the development of outstanding scientists and enable them to...

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SEC_ID: PAR-25-323 05/24/2026
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required)
Award Agency Discretion

The Stephen I. Katz Early Stage Investigator Research Project Grant supports an innovative project that represents a change in res...

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SEC_ID: PA-24-195 05/24/2026
NIH Pathway to Independence Award (Parent K99/R00 Independent Basic Experimental Studies with Humans Required)
Award Agency Discretion

The purpose of the NIH Pathway to Independence Award (K99/R00) program is to increase and maintain a strong cohort of new and tale...

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SEC_ID: PA-24-177 05/24/2026
Mentored Research Scientist Development Award (Parent K01 Independent Basic Experimental Studies with Humans Required)
Award Agency Discretion

The purpose of the NIH Mentored Research Scientist Development Award (K01) is to provide support and protected time (three to five...

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SEC_ID: RFA-HL-26-018 12/23/2027
Catalyze: Product Definition for Small Molecules, Biologics, and Combination Products - Preliminary Product/Lead Series Identification and Combination Product Prototype (R33 - Clinical Trial Not Allowed)
Award Agency Discretion

The goal of the NHLBI Catalyze Program is to provide a comprehensive suite of support and services to facilitate the transition of...

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SEC_ID: RFA-HL-26-017 12/23/2027
Catalyze: Product Definition for Small Molecules, Biologics and Combination Products - Target Identification and Validation, and Preliminary Product/Lead Series Identification (R61/R33 Clinical Trials Not Allowed)
Award Agency Discretion

The goal of the NHLBI Catalyze Program is to provide a comprehensive suite of support and services to facilitate the transition of...

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SEC_ID: PAR-27-015 11/16/2028
Community-Based Participatory Research to Advance Data and Practice Transformation (ADAPT) for Optimizing Oral Health for All (UG3/UH3 Clinical Trial Optional)
Award $300,000

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit UG3/UH3 phased, cooperative agreement research applications...

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SEC_ID: RFA-DE-27-001 10/19/2026
Community Engagement Evaluation and Data Coordination (CEED) Hub to Advance Data and Practice Transformation for Optimizing Oral Health for All (U01, Clinical Trial Not Allowed)
Award $1,000,000

The purpose of this Notice of Funding Opportunity (NOFO) is to seek applications for a Community Engagement Evaluation and Data co...

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SEC_ID: RFA-MH-27-135 10/11/2026
Addressing Methodological Challenges with Clinical Trials of Rapid-Acting Psychotropic Interventional Drugs (RAPIDs) (R01 Clinical Trial Required)
Award $5,500,000

The purpose of this notice of funding opportunity (NOFO) is to elucidate the key components of the therapeutic effects of rapid-ac...

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SEC_ID: PAR-27-083 05/25/2029
NIAID Resource-Related Research Projects (R24 Clinical Trial Not Allowed)
Award Agency Discretion

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SEC_ID: PAR-27-082 05/25/2029
NIAID Investigator Initiated Program Project Applications (P01 Clinical Trial Not Allowed)
Award Agency Discretion

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SEC_ID: RFA-DK-27-146 06/17/2026
New Generation of Glucose Control Technologies Incorporating AI/ML Tools/Strategies (R01 - Clinical Trial Optional)
Award Agency Discretion

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SEC_ID: RFA-MH-27-205 06/09/2026
Single Source: Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ): Data Processing, Analysis, and Coordination Center (DPACC) (U24 Clinical Trial Not Allowed)
Award Agency Discretion

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NIH Frequently Asked Questions

Who can apply for NIH grants?
NIH grants are open to domestic and foreign institutions including universities, hospitals, nonprofits, and small businesses. Some mechanisms (like SBIR) are restricted to small businesses. Individual fellowships require U.S. citizenship or permanent residency.
What is the NIH R01 grant?
The R01 is NIH's flagship research project grant, providing up to $500,000 per year in direct costs for up to 5 years. It supports hypothesis-driven, investigator-initiated research at universities and research institutions.
How long does NIH grant review take?
NIH operates on a three-cycle review system. From submission to award typically takes 9–12 months. Standard due dates are February, June, and October, with funding decisions following about 9 months later.
What is the NIH payline?
The payline is the percentile score cutoff below which grants are typically funded. It varies by institute and year, but commonly falls between the 10th and 20th percentile (lower is better in NIH scoring).
GrantMetric Intelligence Systems — Independent federal grant intelligence platform. Not affiliated with Grants.gov, the U.S. Department of Health & Human Services, or any government agency. Grant data is sourced from the Grants.gov API for informational purposes only; always verify opportunity details directly with the funding agency before applying. Some links on this site are affiliate links — we may earn a commission at no additional cost to you. Full Disclaimer  ·  Last Reviewed: May 2026  ·  Data Methodology