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Mental Health Grants

Federal funding for mental health research, treatment programs, and behavioral health services from SAMHSA, NIMH, and HHS. Covering depression, anxiety, PTSD, substance use, and community mental health.

Active Grants: 70 // Source: Grants.gov // Updated: Daily
About This Topic

Track federal investments in mental health research, crisis services, and community behavioral health.

Active Opportunities (70)

PAR-25-286 01/07/2028
Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R21 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage applications seeking to develop the next genera...

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PAR-25-101 08/11/2027
Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)
Agency HHS-NIH11

The National Institute on Drug Abuse (NIDA) Cutting-Edge Basic Research Award (CEBRA) is designed to foster highly innov...

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PAR-25-347 09/07/2026
Substance Use/Substance Use Disorder Dissertation Research Award (R36 Clinical Trials Not Allowed)
Agency HHS-NIH11

The goal of this NOFO is to support doctoral candidates from a variety of academic disciplines for up to two years for t...

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DE-FOA-0002265 10/14/2030
University Nuclear Leadership Program– Scholarship and Fellowship Support
Agency DOE-ID

A. STATEMENT OF OBJECTIVES This Funding Opportunity Announcement (FOA) is to award multiple cooperative agreements to ac...

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PAR-26-001 05/07/2027
Screening, Brief Intervention and Referral to Treatment or Prevention (SBIRT/P) for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities (R01, Clinical Trial Required)
Agency HHS-NIH11

The Office of Disease Prevention (ODP) and participating National Institutes of Health (NIH) Institutes, Centers, and Of...

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PAR-25-066 09/07/2026
Social disconnection and Suicide Risk in Late Life (R21 Clinical Trial Optional)
Agency HHS-NIH11

This initiative seeks to solicit applications for research projects that address the link between social disconnection i...

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PAR-25-136 01/07/2028
Laboratories to Optimize Digital Health (R01 Clinical Trial Required)
Agency HHS-NIH11

NIMH seeks applications for innovative research projects to test strategies to increase the reach, efficiency, effective...

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PAR-25-204 11/12/2027
NIDA Research Education Program for Clinical Researchers and Clinicians (R25 Clinical Trial Not Allowed)
Agency HHS-NIH11

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The ove...

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PAR-25-281 01/07/2028
Mood and Psychosis Symptoms during the Menopause Transition (R01 Clinical Trial Optional)
Agency HHS-NIH11

The purpose of this Notice of Funding Opportunity (NOFO) is to advance translational research to better understand the e...

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PAR-25-285 10/15/2027
Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required)
Agency HHS-NIH11

This R61/R33 concept complements NIMHs suite of clinical trial NOFOs by supporting feasibility and infrastructure develo...

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PAR-25-177 10/15/2027
Full-Scale Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 - Clinical Trial Required)
Agency HHS-NIH11

Clinical Trials to Test the Effectiveness of Treatment, Preventive, and Services Interventions (R01 Clinical Trial Requi...

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PAR-25-207 01/07/2028
Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)
Agency HHS-NIH11

NIMH seeks applications for research projects to evaluate the effectiveness of therapeutic and service delivery interven...

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PAR-25-291 01/07/2028
Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)
Agency HHS-NIH11

Reissue of RFA-20-351.The purpose of this Notice of Funding Opportunity (NOFO) is to encourage applications to pursue in...

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PAR-25-288 01/07/2028
Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R34 Clinical Trial Required)
Agency HHS-NIH11

The purpose of this NOFO is to build research about the effectiveness, implementation, and optimization of family naviga...

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PAR-25-282 01/07/2028
Mood and Psychosis Symptoms during the Menopause Transition (R21 Clinical Trial Optional)
Agency HHS-NIH11

The purpose of this Notice of Funding Opportunity (NOFO) is to advance translational research to better understand the e...

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PAR-24-297 01/07/2028
Imaging - Science Track Award for Research Transition (I/START) (R03 Clinical Trial Optional)
Agency HHS-NIH11

This Notice of Funding Opportunity Announcement (NOFO) is designed to encourage and facilitate the entry of investigator...

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PAR-25-289 01/07/2028
Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R01 Clinical Trial Required)
Agency HHS-NIH11

The purpose of this NOFO is to build research about the effectiveness, implementation, and optimization of family naviga...

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PAR-25-310 01/07/2027
Accelerating Solutions to Improve Access and Quality of Empirically-Supported Practices for Youth Mental Health (R01 Clinical Trial Optional)
Agency HHS-NIH11

This NOFO is a call to action in response to the mental health crisis in the United States. We seek applications that wi...

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PAR-24-269 02/11/2027
NIDA Animal Genomics Program (U01 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of the NIDA Animal Genetics Program is to identify genetic, genomic, and molecular (epi)genetic variants tha...

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PAR-25-178 10/15/2027
Pilot Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 Clinical Trial Required)
Agency HHS-NIH11

Pilot Effectiveness Trials for Treatment, Preventive and Services Interventions (R01 Clinical Trial Required). As part o...

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PAR-25-040 09/07/2026
Schizophrenia and related disorders during mid- to late-life (R21 Clinical Trial Optional)
Agency HHS-NIH11

Although the majority living with schizophrenia and related disorders are over 35 years old, including those first diagn...

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PAR-25-065 09/07/2026
Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R01 Clinical Trial Optional)
Agency HHS-NIH11

The goal of this Funding Opportunity Announcement (FOA) is to encourage applications for studies that will enhance knowl...

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PAR-25-154 07/16/2026
HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of this notice of funding opportunity (NOFO) is to solicit applications for pilot projects to identify new d...

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CDC-RFA-TP22-2201 02/11/2027
Public Health Crisis Response Cooperative Agreement
Agency HHS-CDC-OPHPR

CDC seeks to enhance the nation’s ability to rapidly mobilize, surge, and respond to public health emergencies (PHEs) ...

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PAR-25-353 10/25/2027
National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U19 Clinical Trial Optional)
Agency HHS-NIH11

Reissue of PAR-20-119. This FOA encourages applications to advance the discovery, preclinical development, and proof of ...

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PAR-25-352 10/25/2027
National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U01 Clinical Trial Optional)
Agency HHS-NIH11

Reissue of PAR-20-118. This Notice of Funding Opportunity (NOFO) encourages applications to advance the discovery, precl...

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PAR-25-283 01/07/2028
Innovative Mental Health Services Research Not Involving Clinical Trials (R01 Clinical Trials Not Allowed)
Agency HHS-NIH11

The purpose of this Notice of Funding Announcement (NOFO) is to encourage innovative research that will inform and suppo...

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PAR-25-284 01/07/2028
Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of this Notice of Funding Announcement (NOFO) is to encourage pilot research that is not an immediate precur...

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PAR-25-290 01/07/2028
Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R01 Clinical Trial Optional)
Agency HHS-NIH11

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage applications to pursue invasive neural recordin...

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RFA-DA-26-034 11/18/2027
Chemical Countermeasures Research Program (CCRP) Initiative: Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids (R01 Clinical Trial Not Allowed)
Agency HHS-NIH11

This notice of funding opportunity (NOFO) will support research towards understanding and mitigating the deleterious eff...

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RFA-ES-25-002 04/20/2027
Environmental Health Sciences Core Centers Program (P30 Clinical Trials Optional)
Agency HHS-NIH11

This Notice of Funding Opportunity Announcement (NOFO) invites grant applications for Environmental Health Sciences Core...

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PAR-25-446 08/21/2028
Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional)
Agency HHS-NIH11

The purpose of this Funding Opportunity (NOFO) is to solicit grant applications to support research on the discovery and...

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PAR-24-027 10/30/2026
Population Assessment of Tobacco and Health (PATH) Study Biospecimen Access (X01)
Agency HHS-NIH11

The Population Assessment of Tobacco and Health (PATH) Study provides the scientific community with biospecimens (urine,...

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PAR-24-089 11/13/2026
NIDA Mentored Clinical Scientist Development Program Award in Substance Use and Substance Use Disorder Research (K12 Clinical Trial Optional)
Agency HHS-NIH11

This funding opportunity announcement (FOA) encourages applications for institutional research career development (K12) ...

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PAR-23-240 05/25/2026
Alcohol and Other Substance Use Research Education Programs for Health Professionals (R25 Clinical Trial Not Allowed)
Agency HHS-NIH11

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The ove...

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PAR-24-210 05/18/2026
Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Centers (P50 Clinical Trial Optional)
Agency HHS-NIH11

This Funding Opportunity Announcement (FOA) invites applications for centers to support transdisciplinary teams of clini...

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PAS-25-236 09/07/2027
D-START: Data Science Track Award for Research Transition (D/START) (R03-Clinical Trial Optional)
Agency HHS-NIH11

Data science is an important cross-cutting research approach in the 2022 - 2026 NIDA Strategic Plan and increasing the c...

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PAR-25-064 09/07/2026
Novel Mechanism Research on Neuropsychiatric Symptoms (NPS) in Alzheimer's Dementia (R21 Clinical Trial Optional)
Agency HHS-NIH11

The goal of this Funding Opportunity Announcement (FOA) is to encourage applications for studies that will enhance knowl...

Health View Details →
PAR-25-287 01/07/2028
Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R01 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage applications seeking to develop the next genera...

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PAR-25-206 01/07/2028
Pilot Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)
Agency HHS-NIH11

NIMH seeks applications for pilot effectiveness projects to evaluate the preliminary effectiveness of therapeutic and se...

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PAR-25-226 11/19/2026
Seamless Early-Stage Clinical Drug Development (Phase 1 to 2a) for Novel therapeutic Agents for the Spectrum of Alzheimer's Disease (AD) and AD-related Dementias (ADRD) (UG3/UH3 Clinical Trial Required)
Agency HHS-NIH11

The purpose of this Notice of Funding Opportunity (NOFO) is to invite applications that bundle independent protocols for...

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PAR-25-180 10/15/2027
First in Human and Early Stage Clinical Trials of Novel Investigational Drugs or Neuromodulatory Device-based Interventions for Psychiatric Disorders (U01 Clinical Trial Required)
Agency HHS-NIH11

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage cooperative agreement applications to support e...

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PAR-25-039 09/07/2026
Schizophrenia and related disorders during mid- to late-life (R01 Clinical Trial Optional)
Agency HHS-NIH11

Although the majority living with schizophrenia and related disorders are over 35 years old, including those first diagn...

Health View Details →
PAR-25-067 09/07/2026
Social disconnection and Suicide Risk in Late Life (R01 Clinical Trial Optional)
Agency HHS-NIH11

This initiative seeks to solicit applications for research projects that address the link between social disconnection i...

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RFA-DA-26-055 12/03/2027
Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of this Notice of Opportunity Announcement (NOFO) is to invite applications proposing the innovative analysi...

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RFA-DA-26-056 12/03/2027
Accelerating the Pace of Substance Use Research Using Existing Data (R21 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of this notice of funding opportunity (NOFO) is to invite applications proposing the innovative analysis of ...

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VA-FOX-SP-FY2027 06/12/2026
Staff Sergeant Fox Suicide Prevention Grant Program Funding Opportunity
Agency VA-OMHSP

Description: The Department of Veterans Affairs (VA) is announcing the availability of funds for new and renewing suicid...

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CMS-2Q2-26-001 06/03/2026
Innovation in Behavioral Health (IBH)
Agency HHS-CMS

The Innovation in Behavioral Health (IBH) Model (the “Model”) for Cohort II Recipients is a seven-year, voluntary se...

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RFA-DA-25-060 03/05/2027
High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional)
Agency HHS-NIH11

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of H...

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RFA-DA-25-024 03/06/2027
High Priority HIV and Substance Use Research (R01 Clinical Trial Optional)
Agency HHS-NIH11

The purpose of this Funding Opportunity Announcement (FOA) is to support high priority research at the intersection of H...

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PAR-24-233 05/25/2026
NIMH Research Education Mentoring Program for HIV Researchers (R25 Clinical Trial Not Allowed)
Agency HHS-NIH11

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The ove...

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PAR-24-164 05/25/2026
Developmental AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional)
Agency HHS-NIH11

The National Institute of Mental Health (NIMH) Division of AIDS Research (DAR) encourages applications for Center Core g...

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PAR-24-165 05/25/2026
AIDS Research Center on Mental Health and HIV/AIDS (P30 Clinical Trial Optional)
Agency HHS-NIH11

The National Institute of Mental Health (NIMH) Division of AIDS Research (DAR) encourages applications for Center Core g...

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O-OJJDP-2025-172517 05/08/2026
OJJDP FY25 Expanding Youth Access to Community-Based Treatment
Agency USDOJ-OJP-OJJDP

This NOFO supports community-based treatment programs serving youth under the age of 18 with substance use disorder (SUD...

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O-OJJDP-2025-172510 05/08/2026
OJJDP FY25 Opioid Affected Youth Initiative
Agency USDOJ-OJP-OJJDP

This NOFO will support states, local and Tribal jurisdictions to implement prevention and intervention programs and stra...

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O-BJA-2025-172488 05/08/2026
BJA FY25 Second Chance Act Family-Based Substance Use Disorder Treatment Program
Agency USDOJ-OJP-BJA

This NOFO will provide funding to deliver treatment and recovery support services for parents with substance use disorde...

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O-BJA-2025-172508 05/08/2026
BJA FY25 Residential Substance Abuse Treatment (RSAT) for State Prisoners Training and Technical Assistance Program
Agency USDOJ-OJP-BJA

This NOFO will provide training and technical assistance (TTA) to state and local grantees of the Residential Substance ...

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CDC-RFA-CE-26-0110 06/08/2026
Comprehensive Addiction and Recovery Act (CARA)
Agency HHS-CDC-NCIPC

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PA-FPH-27-001 01/09/2027
Title X Family Planning Services Grants
Agency HHS-OPHS

The Office of Population Affairs (OPA) announces the anticipated availability of funds for Fiscal Year (FY) 2027 grants ...

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O-BJA-2025-172498 05/27/2026
BJA FY25 De-escalation and Crisis Response Training Program
Agency USDOJ-OJP-BJA

This NOFO supports state, local, and tribal governments, law enforcement agencies, correctional facilities, probation an...

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O-BJA-2025-172582 05/12/2026
BJA FY25 Byrne State Crisis Intervention Formula Program
Agency USDOJ-OJP-BJA

OJP is committed to advancing work that furthers DOJ’s mission to uphold the rule of law, to keep our country safe, an...

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FR-6900-N-33 05/26/2026
Comprehensive Housing Counseling (CHC) and the Housing Counseling Training (HCT) NOFO (FY2025)
Agency HUD

The purpose of HUD"s Housing Counseling Grant Program is to provide funds to HUD-approved housing counseling agencies th...

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PAR-27-081 03/05/2027
Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of this Notice of Funding Opportunity (NOFO) is to support investigators who have the interest and capabilit...

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O-BJA-2025-172542 05/12/2026
BJA FY25 Edward Byrne Memorial Justice Assistance Grant (JAG) Program – Local Formula
Agency USDOJ-OJP-BJA

OJP is committed to advancing work that furthers DOJ’s mission to uphold the rule of law, to keep our country safe, an...

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TCEP-2027 05/31/2026
Tax Counseling for the Elderly (TCE)
Agency USDOT-IRS-TCE

The Tax Counseling for the Elderly (TCE) Program offers FREE tax help to individuals who are age 60 or older. Section 16...

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PAS-BF-FY26-APS-001 07/03/2026
U.S. Embassy in Ouagadougou, Burkina Faso PDS Annual Program Statement
Agency DOS-BFA

The U.S. Department of State’s Embassy Ouagadougou is pleased to announce an open competition for organizations to sub...

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USDA-FAS-10960-0700-10-25-0010 05/14/2026
Coordinating Agricultural Development & Innovation (CADI) Armenia Exchanges: U.S. Food Safety Regulations and Standards Training Program
Agency USDA-FAS

USDA/FAS is requesting the design and delivery of a training program on U.S. Food Safety regulations and standards for 9...

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O-BJA-2025-172581 05/13/2026
BJA FY25 Comprehensive Opioid, Stimulant, and Substance Use Program (COSSUP) Investigations Training and Technical Assistance (TTA)
Agency USDOJ-OJP-BJA

This NOFO will support specialized training and technical assistance (TTA) to Comprehensive Opioid, Stimulant, and Subst...

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O-BJA-2025-172485 05/08/2026
BJA FY25 Comprehensive Opioid, Stimulant, and Substance Use, Site-Based Program
Agency USDOJ-OJP-BJA

This funding opportunity seeks to develop, implement or expand comprehensive programs in response to overdose deaths, il...

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RFA-MH-27-205 06/09/2026
Single Source: Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ): Data Processing, Analysis, and Coordination Center (DPACC) (U24 Clinical Trial Not Allowed)
Agency HHS-NIH11

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About This Funding Category

Federal mental health funding flows through two parallel channels: formula allocations distributed to states and competitive grants awarded directly to qualifying organizations. SAMHSA's Community Mental Health Services Block Grant distributes approximately $700 million annually to states, which sub-award to community mental health centers and behavioral health nonprofits. Competitive SAMHSA grants — including Certified Community Behavioral Health Clinic (CCBHC) expansion awards, Crisis Services grants, and Opioid Treatment Program grants — are awarded directly to organizations meeting specific eligibility criteria. NIMH, part of NIH, funds mental health research at universities and research institutions through R01, R21, and specialized training grants. The 988 Suicide and Crisis Lifeline funding, administered by SAMHSA, supports crisis centers and call center operations across the country. For community organizations without research capacity, SAMHSA's Health Resources and Services Administration (HRSA) behavioral health workforce grants and the Substance Abuse Prevention Block Grant offer the most accessible entry points into federal behavioral health funding.

Frequently Asked Questions

What agency funds mental health grants?
SAMHSA (Substance Abuse and Mental Health Services Administration) is the primary funder of community mental health programs. NIMH (National Institute of Mental Health), part of NIH, funds mental health research. HHS also administers block grants for state mental health services.
Can community mental health centers apply for federal grants?
Yes. SAMHSA's Certified Community Behavioral Health Clinic (CCBHC) program, Community Mental Health Services Block Grant, and Substance Abuse Prevention and Treatment Block Grant are all accessible to community mental health organizations.
What is the 988 Suicide & Crisis Lifeline grant?
SAMHSA provides funding to states to staff and operate the 988 Suicide & Crisis Lifeline network. Crisis centers, behavioral health organizations, and state agencies can apply for operational funding through SAMHSA's crisis services grant portfolio.
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GrantMetric Intelligence Systems — Independent federal grant intelligence platform. Not affiliated with Grants.gov, the U.S. Department of Health & Human Services, or any government agency. Grant data is sourced from the Grants.gov API for informational purposes only; always verify opportunity details directly with the funding agency before applying. Some links on this site are affiliate links — we may earn a commission at no additional cost to you. Full Disclaimer  ·  Last Reviewed: May 2026  ·  Data Methodology