GrantMetric / New Grants / December 2024
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New Federal Grants — December 2024

71 federal grant opportunities posted in December 2024, sourced live from Grants.gov. Covers health, technology, environment, energy, defense, and more.

Posted in December 2024: 71 // Source: Grants.gov // Updated: Daily
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About December 2024 Federal Grant Postings

Federal agencies post Notices of Funding Opportunity (NOFOs) throughout the year. Grants posted in December 2024 represent active funding from NIH, NSF, DOD, EPA, USDA, HHS, DOE, and other federal agencies. Each posting includes the award ceiling, eligibility requirements, and application deadline — all sourced directly from Grants.gov.

Newly posted grants are typically open for 30–90 days. High-priority programs from NIH and DOD often close faster — monitoring monthly postings ensures your organization does not miss time-sensitive opportunities. Bookmark this page and check back as new grants are added throughout the month.

How to use this list: Click any grant to view the full funding opportunity details including award ceiling, eligibility criteria, application instructions, and AI-generated briefing. Use the sector tags to identify relevant programs. All close dates are displayed in MM/DD/YYYY format and sourced directly from the official Grants.gov registry.

Grants Posted in December 2024 (71)

PAR-25-337 01/07/2028
Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Optional)
Agency HHS-NIH11

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to stimulate efforts to t...

Posted: 12/31/2024 View Details →
PAR-25-338 01/07/2028
Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Not Allowed)
Agency HHS-NIH11

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to stimulate efforts to t...

Posted: 12/31/2024 View Details →
PAR-25-101 08/11/2027
Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)
Agency HHS-NIH11

The National Institute on Drug Abuse (NIDA) Cutting-Edge Basic Research Award (CEBRA) is designed to foster highly innov...

Posted: 12/30/2024 View Details →
PAR-25-374 05/07/2028
Translational Bioinformatics and Experimental Approaches to Advance Drug Repositioning and Combination Therapy Development for Alzheimers Disease and Related Dementias (R01 Clinical Trial Not Allowed)
Agency HHS-NIH11

This Notice of Funding Opportunity (NOFO) invites applications that propose to use mouse models to conduct rigorous prec...

Posted: 12/30/2024 View Details →
PAR-25-283 01/07/2028
Innovative Mental Health Services Research Not Involving Clinical Trials (R01 Clinical Trials Not Allowed)
Agency HHS-NIH11

The purpose of this Notice of Funding Announcement (NOFO) is to encourage innovative research that will inform and suppo...

Posted: 12/30/2024 View Details →
PAR-25-284 01/07/2028
Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of this Notice of Funding Announcement (NOFO) is to encourage pilot research that is not an immediate precur...

Posted: 12/30/2024 View Details →
PAR-25-362 11/05/2028
Early Immune System Development and Ontogeny (R01 Clinical Trial Optional)
Agency HHS-NIH11

The purpose of this Notice of Funding Opportunity (NOFO) is tofurther elucidate the mechanisms of early immune developme...

Posted: 12/30/2024 View Details →
25-525 06/01/2026
Antarctic Research Requiring U.S. Antarctic Program (USAP) Support for Fieldwork
Agency NSF

Through this solicitation, the Antarctic Sciences Section (ANT) of the Office of Polar Programs (OPP) funds cutting-edge...

Posted: 12/22/2024 View Details →
PAR-25-194 09/28/2027
Limited Competition: Ruth L. Kirschstein National Research Service Award (NRSA) Predoctoral Research Training Grant for the Clinical and Translational Science Awards (CTSA) Program (T32 Clinical Trial Not Allowed)
Agency HHS-NIH11

The National Center for Advancing Translational Sciences (NCATS) will award Ruth L. Kirschstein National Research Servic...

Posted: 12/19/2024 View Details →
PAR-25-195 09/28/2027
Limited Competition: Ruth L. Kirschstein National Research Service Award (NRSA) Postdoctoral Research Training Grant for the Clinical and Translational Science Awards (CTSA) Program (T32 Clinical Trial Not Allowed)
Agency HHS-NIH11

The National Center for Advancing Translational Sciences (NCATS) will award Ruth L. Kirschstein National Research Servic...

Posted: 12/19/2024 View Details →
25-526 06/01/2026
Antarctic Research Not Requiring U.S. Antarctic Program (USAP) Field Support
Agency NSF

Through this solicitation, the Antarctic Sciences Section (ANT) of the Office of Polar Programs (OPP) funds cutting-edge...

Posted: 12/19/2024 View Details →
PA-25-302 01/07/2028
NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed)
Agency HHS-NIH11

The NIH Small Research Grant Program supports small research projects that can be carried out in a short period of time ...

Posted: 12/18/2024 View Details →
PAR-25-032 01/07/2027
NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)
Agency HHS-NIH11

This Notice of Funding Opportunity Announcement (NOFO) intends to supports studies that are both necessary and sufficien...

Posted: 12/18/2024 View Details →
PAR-25-327 10/08/2027
Translational Efforts to Advance Gene-based Therapies for Ultra-Rare Neurological and Neuromuscular Disorders (U01 - Clinical Trial Optional)
Agency HHS-NIH11

The Ultra-Rare Gene-Based Therapy (URGenT) network supports Investigational New Drug (IND)-enabling studies and planning...

Posted: 12/18/2024 View Details →
PA-25-301 01/07/2028
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)
Agency HHS-NIH11

The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific ...

Posted: 12/18/2024 View Details →
PA-25-305 01/07/2028
NIH Research Project Grant (Parent R01 Clinical Trial Required)
Agency HHS-NIH11

The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific ...

Posted: 12/18/2024 View Details →
PA-25-304 01/07/2028
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)
Agency HHS-NIH11

The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support fo...

Posted: 12/18/2024 View Details →
PA-25-306 01/07/2028
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)
Agency HHS-NIH11

The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support fo...

Posted: 12/18/2024 View Details →
PA-25-303 05/24/2026
NIH Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required)
Agency HHS-NIH11

The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific ...

Posted: 12/18/2024 View Details →
PA-25-307 05/24/2026
NIH Exploratory/Developmental Research Project Grant (Parent R21 Basic Experimental Studies with Humans Required)
Agency HHS-NIH11

The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support fo...

Posted: 12/18/2024 View Details →
PAR-25-311 11/15/2027
Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Women, and Persons with Disabilities (UG3/UH3 - Clinical Trial Optional)
Agency HHS-NIH11

The purpose of this Notice of Funding Opportunity (NOFO) is to leverage NICHD clinical research Network infrastructure r...

Posted: 12/16/2024 View Details →
PAR-25-336 11/15/2027
Toward Translation of Nanotechnology Cancer Interventions (TTNCI; R01 Clinical Trial Not Allowed)
Agency HHS-NIH11

Through this Notice of Funding Opportunity (NOFO), entitled "Toward Translation of Nanotechnology Cancer Interventions" ...

Posted: 12/16/2024 View Details →
RFA-HG-25-009 02/26/2027
Supporting Talented Early Career Researchers in Genomics (R01 Clinical Trial Optional)
Agency HHS-NIH11

This Funding Opportunity Announcement is intended to identify and support research projects by exceptionally promising E...

Posted: 12/16/2024 View Details →
RFA-DC-25-002 10/12/2027
NIDCD Research Grants for Translating Basic Research into Clinical Practice (R01 Clinical Trial Optional)
Agency HHS-NIH11

This Funding Opportunity Announcement (FOA) is intended to provide an avenue for basic scientists, clinicians and clinic...

Posted: 12/16/2024 View Details →
PAS-25-236 09/07/2027
D-START: Data Science Track Award for Research Transition (D/START) (R03-Clinical Trial Optional)
Agency HHS-NIH11

Data science is an important cross-cutting research approach in the 2022 - 2026 NIDA Strategic Plan and increasing the c...

Posted: 12/16/2024 View Details →
25-523 07/21/2026
EPSCoR Research Infrastructure Improvement Program: EPSCoR Collaborations for Optimizing Research Ecosystems
Agency NSF

The Established Program to Stimulate Competitive Research (EPSCoR) supports the U.S. National Science Foundation (NSF) m...

Posted: 12/14/2024 View Details →
25-522 08/11/2026
EPSCoR Research Infrastructure Improvement Program: EPSCoR Research Incubators for STEM Excellence
Agency NSF

The Established Program to Stimulate Competitive Research (EPSCoR) supports the mission of the U.S. National Science Fou...

Posted: 12/14/2024 View Details →
PAR-25-247 09/25/2026
Institutional Training Programs to Advance Translational Research on Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) (T32 Clinical Trial Not Allowed)
Agency HHS-NIH11

The specific purpose of this Notice of Funding Opportunity (NOFO) is to promote the development of a diverse, interdisci...

Posted: 12/13/2024 View Details →
PAR-25-317 05/08/2027
Risk and Protective Factors of Family Health and Family Level Interventions (R01 Clinical Trial Optional)
Agency HHS-NIH11

The purpose of this initiative is to advance the science of minority health and health disparities by supporting researc...

Posted: 12/13/2024 View Details →
PAR-25-325 09/10/2027
Integrating Biospecimen Science Approaches into Clinical Assay Development (U01 Clinical Trial Not Allowed)
Agency HHS-NIH11

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to support extramural res...

Posted: 12/13/2024 View Details →
PAR-25-155 10/19/2026
Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional)
Agency HHS-NIH11

The purpose of this NOFO is to enhance the capability of NCATS CTSA Program KL2 scholars and recipients of re-entry supp...

Posted: 12/11/2024 View Details →
PAR-25-154 07/16/2026
HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of this notice of funding opportunity (NOFO) is to solicit applications for pilot projects to identify new d...

Posted: 12/11/2024 View Details →
PAR-25-296 10/19/2027
Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional)
Agency HHS-NIH11

The CTSA Collaborative and Innovative Acceleration Award (CCIA) aims to accelerate the pace of translational research by...

Posted: 12/11/2024 View Details →
PAR-25-346 01/07/2028
Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed)
Agency HHS-NIH11

Through this engineering-oriented Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to e...

Posted: 12/11/2024 View Details →
PAR-25-156 09/28/2026
Limited Competition: High Impact Specialized Innovation Programs in Clinical and Translational Science (RC2 Clinical Trials Optional)
Agency HHS-NIH11

The purpose of the High Impact Specialized Innovation Programs (SIPs) is to support the development and demonstration of...

Posted: 12/10/2024 View Details →
PAR-25-157 06/18/2026
Awards Supporting Cutting-Edge Technologies for Translational Science (ASCETTS) (R21 Clinical Trials Not Allowed)
Agency HHS-NIH11

The National Center for Advancing Translational Sciences (NCATS) invites applications for the Awards Supporting Cutting-...

Posted: 12/10/2024 View Details →
PAR-25-196 09/28/2027
Limited Competition: Mentored Research Career Development Program Award in Clinical and Translational Science Awards (CTSA) Program (K12 Clinical Trial Optional)
Agency HHS-NIH11

The National Center for Advancing Translational Sciences (NCATS) will award Institutional Research Career Development (K...

Posted: 12/10/2024 View Details →
PAR-25-321 01/07/2028
Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Optional)
Agency HHS-NIH11

Through this engineering-oriented Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to e...

Posted: 12/10/2024 View Details →
25-516 See Registry
Chemical Evolution of the Solid Earth and Volcanology
Agency NSF

The Chemical Evolution of the Solid Earth and Volcanology (CESEV) program aims to advance fundamental knowledge about th...

Posted: 12/10/2024 View Details →
PAR-25-197 05/28/2027
Limited Competition: NCATS Clinical and Translational Science Award (CTSA) Program Research Education Grants Programs (R25 - Clinical Trial Not Allowed)
Agency HHS-NIH11

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The ove...

Posted: 12/09/2024 View Details →
PAR-25-141 03/04/2027
NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
Agency HHS-NIH11

This NIAMS Clinical Trial Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) PAR, a re-issue of PAR-...

Posted: 12/09/2024 View Details →
PAR-24-280 11/02/2026
Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed)
Agency HHS-NIH11

This Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowe...

Posted: 12/09/2024 View Details →
RFA-EY-25-001 06/15/2026
BRAIN Initiative: New Concepts and Early-Stage Research for Recording and Modulation in the Nervous System (R21) (Clinical Trial Not Allowed)
Agency HHS-NIH11

A central goal of the BRAIN Initiative is to understand how electrical and chemical signals code information in neural c...

Posted: 12/09/2024 View Details →
PAR-24-279 11/02/2026
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required)
Agency HHS-NIH11

This Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required) ...

Posted: 12/09/2024 View Details →
25-518 See Registry
Structure and Physics of the Solid Earth
Agency NSF

The Structure and Physics of the Solid Earth Program (SPSE) aims to advance fundamental knowledge about the ongoing dyna...

Posted: 12/07/2024 View Details →
25-519 See Registry
Water, Landscape, and Critical Zone Processes
Agency NSF

The Water, Landscape, and Critical Zone Processes program supports research on the Earth's near-surface environment and ...

Posted: 12/07/2024 View Details →
25-517 See Registry
Life and Environments Through Time
Agency NSF

The Life and Environments Through Time (LET) program supports research that advances knowledge about the patterns and pr...

Posted: 12/07/2024 View Details →
PAR-25-298 01/07/2028
Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of the Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools is to ...

Posted: 12/06/2024 View Details →
PAR-24-330 09/07/2027
Interventions to Reduce Sleep Health Disparities (R01 - Clinical Trials Optional)
Agency HHS-NIH11

This PAR is being reissued in accordance with the simplified review criteria in effect for application due dates after J...

Posted: 12/06/2024 View Details →
RFA-TR-25-002 06/02/2026
Preclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed)
Agency HHS-NIH11

This notice of funding opportunity (NOFO) provides funding to conduct efficacy studies in an established rare disease pr...

Posted: 12/06/2024 View Details →
PAR-25-100 05/07/2027
Pilot Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R34 Clinical Trial Optional)
Agency HHS-NIH11

This Notice of Funding Opportunity (NOFO) encourages pilot and preliminary research in preparation for larger-scale serv...

Posted: 12/06/2024 View Details →
25-515 09/28/2026
Security, Privacy, and Trust in Cyberspace
Agency NSF

Our world is at a pivotal moment where the boundaries dividing the physical and social worlds from the cyber world have ...

Posted: 12/06/2024 View Details →
PAR-25-025 01/07/2027
NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)
Agency HHS-NIH11

The objective of this funding opportunity is to support investigator-initiated, phase I clinical trials for diagnostic a...

Posted: 12/05/2024 View Details →
PAR-25-026 01/07/2027
NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)
Agency HHS-NIH11

The objective of this funding opportunity is to support investigator-initiated, Phase I clinical trials for diagnostic a...

Posted: 12/05/2024 View Details →
PAR-25-299 01/07/2028
Interventions to Address Disparities in Liver Diseases and Liver Cancer (R01 - Clinical Trials Optional)
Agency HHS-NIH11

This initiative will support multi-level and/or multi-domain intervention research to reduce disparities in liver diseas...

Posted: 12/05/2024 View Details →
RFA-DA-26-055 12/03/2027
Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of this Notice of Opportunity Announcement (NOFO) is to invite applications proposing the innovative analysi...

Posted: 12/05/2024 View Details →
RFA-DA-26-056 12/03/2027
Accelerating the Pace of Substance Use Research Using Existing Data (R21 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of this notice of funding opportunity (NOFO) is to invite applications proposing the innovative analysis of ...

Posted: 12/05/2024 View Details →
PAR-25-297 11/05/2027
Alzheimer's Drug-Development Program (U01 Clinical Trial Optional)
Agency HHS-NIH11

The goal of this Notice of Funding Opportunity (NOFO) is to provide funding support for the pre-clinical and early stage...

Posted: 12/04/2024 View Details →
PAR-25-251 01/07/2028
NIAID Career Transition Award (K22 Independent Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of the NIAID Career Transition Award program is to assist postdoctoral fellows' transition to positions of a...

Posted: 12/03/2024 View Details →
PAR-25-310 01/07/2027
Accelerating Solutions to Improve Access and Quality of Empirically-Supported Practices for Youth Mental Health (R01 Clinical Trial Optional)
Agency HHS-NIH11

This NOFO is a call to action in response to the mental health crisis in the United States. We seek applications that wi...

Posted: 12/03/2024 View Details →
25-514 03/02/2027
NSF Scholarships in Science, Technology, Engineering, and Mathematics Program
Agency NSF

The main goal of the S-STEM program is to enable academically talented, low-income students to pursue successful careers...

Posted: 12/03/2024 View Details →
PAR-25-265 11/16/2027
Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R01 - Clinical Trial Optional)
Agency HHS-NIH11

This FOA encourages research relevant to the development of novel screening approaches and/or therapeutic interventions ...

Posted: 12/02/2024 View Details →
PAR-25-271 11/13/2026
NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required)
Agency HHS-NIH11

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated mid-phase clinical trials o...

Posted: 12/02/2024 View Details →
PAR-25-134 01/07/2028
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)
Agency HHS-NIH11

The purpose of this Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutionsis to support small...

Posted: 12/02/2024 View Details →
FA875025S7001 12/05/2028
FOUNDATIONS OF TRUSTED SYSTEMS
Agency DOD-AFRL

https://sam.gov/opp/6a5d1f379ee34a0395eeb98e220c730c/view

Posted: 12/02/2024 View Details →
PAR-25-188 01/06/2028
NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
Agency HHS-NIH11

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage UG3/UH3 phased cooperative agreement research a...

Posted: 12/02/2024 View Details →
PAR-25-216 11/12/2027
Career Transition Award for NINDS Intramural Clinician-Scientists (K22 Clinical Trial Required)
Agency HHS-NIH11

The objective of the NIH Career Transition Award (K22) is to provide support to outstanding basic or clinical investigat...

Posted: 12/02/2024 View Details →
PAR-25-215 11/12/2027
Career Transition Award for NINDS Intramural Clinician-Scientists (K22 Clinical Trial Not Allowed)
Agency HHS-NIH11

The objective of the NIH Career Transition Award (K22) is to provide support to outstanding basic or clinical investigat...

Posted: 12/02/2024 View Details →
PAR-25-266 11/16/2027
Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R21 - Clinical Trial Optional)
Agency HHS-NIH11

This FOA encourages research relevant to the development of novel screening approaches and/or therapeutic interventions ...

Posted: 12/02/2024 View Details →
PAR-25-269 11/13/2026
NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33 Clinical Trial Required)
Agency HHS-NIH11

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical tria...

Posted: 12/02/2024 View Details →
PAR-25-270 11/13/2026
NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)
Agency HHS-NIH11

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical tria...

Posted: 12/02/2024 View Details →
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GrantMetric Intelligence Systems — Independent federal grant intelligence platform. Not affiliated with Grants.gov, the U.S. Department of Health & Human Services, or any government agency. Grant data is sourced from the Grants.gov API for informational purposes only; always verify opportunity details directly with the funding agency before applying. Some links on this site are affiliate links — we may earn a commission at no additional cost to you. Full Disclaimer  ·  Last Reviewed: May 2026  ·  Data Methodology